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Basal Cell Carcinoma - Superficial

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Synonyms: erythmatoid or pagetoid basal cell carcinoma

This article should be read in conjunction with the article Basal Cell Carcinoma (Rodent Ulcer).

Superficial basal cell carcinoma is a clinical subtype of basal cell carcinoma (BCC).

Epidemiology1
  • An Australian study showed an incidence for superficial BCCs of 336/100,000 men and 251/100,000 women per annum.2
  • Superficial BCCs occur at a younger age than other BCC variants, particularly in women.
Presentation

There is a good photograph of a superficial BCC on the DermIS website.3

  • Equal distribution over face, trunks and limbs - although site of predilection seems to vary according to sex (head in women, trunk in men).4
  • Usually flat, pink to red-brown scaly plaque with central clearing and a thread-like border. If stretched, a rolled edge can be seen.
  • Very slow growing but over months to years it may grow to become several centimetres in diameter.
  • It may bleed or weep.
Prognosis1,5,6
  • Usually not an aggressive form of BCC; rarely becomes invasive and extremely rarely metastasises.
  • Compared to nodular BCCs, less likely to erode and ulcerate.
  • Recurrent tumours have poorer cure rates compared to the treatment of primary tumours.
  • Having had a BCC, increased risk of developing further lesions, particularly in those presenting with truncal lesions (hazard ratio 1.58).
  • Increased risk of malignant melanoma, presumably as sun exposure is important in the causation of both.

Document references
  1. Wong CS, Strange RC, Lear JT; Basal cell carcinoma. BMJ. 2003 Oct 4;327(7418):794-8.
  2. Raasch BA, Buettner PG, Garbe C; Basal cell carcinoma: histological classification and body-site distribution. Br J Dermatol. 2006 Aug;155(2):401-7. [abstract]
  3. DermIS; superficial basal cell carcinoma; image
  4. Scrivener Y, Grosshans E, Cribier B; Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002 Jul;147(1):41-7. [abstract]
  5. Ramsey ML; Basal Cell Carcinoma. eMedicine, January 2008.
  6. Guidelines for the management of basal cell carcinoma, British Association of Dermatologists (2008)
Acknowledgements EMIS is grateful to Dr Colin Tidy for writing this article and to Dr Chloe Borton for earlier versions. The final copy has passed scrutiny by the independent Mentor GP reviewing team. ©EMIS 2009.
DocID: 4085
Document Version: 21
DocRef: bgp26011
Last Updated: 9 Jan 2009
Review Date: 9 Jan 2011

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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