Haemangiomata of Skin

Haemangiomata appear as red to purple papules or plaques with a normal epithelial surface.¹ Compression leads to partial emptying and the colour becomes less prominent. They may occur at any age, and remain fixed in site and size. There are various types:²

• Capillary naevus - this is a salmon-pink patch seen on the neck in up to 40% of infants. It may not fade, but is often covered by hair. Facial lesions tend to fade in the first year of life.¹
• Port-wine stain - this is a lesion lined with endothelial cells and containing blood vessels. It does not regress with age. It may be associated with Sturge-Weber syndrome (port-wine stain of the face, angiomas of the leptomeninges and choroid, and late glaucoma) and Klippel-Trenaunay-Weber syndrome (local overgrowth of soft tissue and bone in an extremity or more extensive area, port-wine stain, varicose veins, cutaneous angiomata and other variable features).¹
• Vin rose patch - this is a pale pink lesion appearing as a birth mark due to dilatation of the sub-papillary dermal plexus.
• Cavernous haemangioma - this is also known as a strawberry naevus. It tends to regress after the first year of life and normally resolves completely after the age of 4 or 5. Persistent lesions or those causing obstruction of vision may require treatment.³
• Cherry angioma - also known as Campbell de Morgan's spots, they appear on the abdomen and chest and are red, slightly elevated keratoangiomata. They do not fade with pressure.⁴
• Telangiectasia - these are permanent dilatations of groups of capillaries or venules. They may be inherited or associated with atopy, sun damage, connective tissue disease, raised oestrogen levels or venous hypertension.⁵

The compression test is useful, or the lesion can be examined with a dermatoscope (an instrument which assists in close examination of the skin) and the blood filled cavities observed.⁶ Sometimes a haemangioma may be confused with a malignant melanoma, if both are dark in colour and of recent origin. Thye can be differentiated by excision biopsy. Cambell de Morgan spots (cherry angiomas) are a type of haemangiomata which remain small and increase in number with age. A strawberry mark/naevus is a proliferating haemangioma that occurs in the first year of life and then regresses thereafter.

Most haemangiomata require no treatment unless the patient is concerned about their appearance.
Port-wine stains are usually treated by camouflage or by laser therapy.⁷Cavernous haemangiomata may require treatment if affecting normal development, such as development of binocular vision. Treatment options include systemic or local steroids, sclerosants, interferon or laser treatment.²
Strawberry naevi causing complications (bleeding, obstructing of other organs, rapid growth) may be treated with laser therapy.

Lesions remain fixed but cause no problems.

Referral should be considered if diagnosis is in doubt or excision is required