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Self-monitoring Blood Glucose in Diabetes Mellitus

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Self-monitoring of blood glucose (SMBG) provides people with diabetes mellitus with an accurate method of measuring blood glucose concentrations and therefore detecting both hyperglycaemia or hypoglycaemia. There is currently a great deal of debate about the need and frequency of blood glucose monitoring in diabetes mellitus. The debate is focused on the balance between the high and rising NHS expenditure on blood glucose monitoring and the importance of the involvement and empowerment of people with diabetes in their own care.1 Although glucose meters are not prescribable at NHS expense, they are often provided free to patients from the manufacturers on the basis of income made from the testing strips, which are prescribable at NHS expense and each type of testing strip is specific to each monitor.

NICE recommendations for patients with type 2 diabetes2
  • Offer self-monitoring of plasma glucose to a person newly diagnosed with type 2 diabetes only as an integral part of his or her self-management education.
  • Discuss its purpose and agree how it should be interpreted and acted upon.
  • Self-monitoring of plasma glucose should be available:
    • To those on insulin treatment.
    • To those on oral glucose-lowering medications to provide information on hypoglycaemia.
    • To assess changes in glucose control resulting from medications and lifestyle changes.
    • To monitor changes during intercurrent illness.
    • To ensure safety during activities, including driving.
  • Assess at least annually and in a structured way:
    • Self-monitoring skills.
    • The quality and appropriate frequency of testing.
    • The use made of the results obtained.
    • The impact on quality of life.
    • The continued benefit.
    • The equipment used.
  • If self-monitoring is appropriate but blood glucose monitoring is unacceptable to the individual, discuss the use of urine glucose monitoring. See separate record Urine Glucose Monitoring in Diabetes Mellitus.

Requirements for blood glucose testing
  • Patients should be given adequate training in self-monitoring techniques, including interpretation of results and appropriate action when required.
  • Many people with diabetes provide books full of results but still don't fully understand the implications of the results or have a full understanding of diabetes mellitus and its implications and management.
  • Glucose testing meters should be checked and re-calibrated at recommended intervals to ensure accuracy.
Role of blood glucose testing
  • Strict control of blood glucose levels improves the outcomes in patients with either type I or type 2 diabetes.
  • However, it is not clear whether self-monitoring contributes to this improvement.3
  • For SMBG to be most useful, it should form part of a wider programme of management.
  • Self-monitoring is most appropriate for patients with type I diabetes or type 2 diabetes who use insulin regimes and adjust their dose as a result of blood glucose testing, and for all diabetic patients when they have intercurrent illness.
  • There are no specific national guidelines available and the need and extent of home glucose testing will depend on the treatment required for diabetes, the degree of glycaemic control and the preferences and needs of each individual.4

Patients using insulin1

  • Patients who are using insulin but have good glycaemic control still need to perform blood tests regularly.
  • The regime should be appropriate and acceptable to each individual patient.
  • Those using twice-daily insulin therapy should be educated to undertake SMBG at least twice daily, varying the time between fasting, pre-meal and post-meal, to help build up a profile of glycaemic control throughout the day. Some patients prefer to perform frequent tests on 2 or 3 days in the week and then again only if concerned about possible hypoglycaemia.
  • Frequent self-monitoring is required during illness (least four times a day).
  • Ideally, patients who alter insulin doses at mealtimes should be encouraged to monitor at least four times daily.
  • Patients with symptoms of nocturnal hypoglycaemia or resistant morning hyperglycaemia should measure blood glucose levels in the early hours of the morning (between 2 am and 3 am).
  • Patients who are pregnant or hoping to become pregnant, or using insulin pump therapy should monitor their blood glucose levels between 4-6 times daily.
  • Patients with type 2 diabetes on insulin with oral hypoglycaemic agents should be encouraged to self-monitor at least once daily, varying the time between fasting, pre-meal and post-meal, to identify trends.

People with type 2 diabetes who are not using insulin

  • There is no evidence that blood testing is more effective than urine testing at improving blood glucose control in people with type 2 diabetes.3
  • Many people with type 2 diabetes, especially those who are diet-controlled, do not need to perform home blood glucose monitoring. There is no risk of hypoglycaemia, and glycaemic control is better and adequately monitored by regular testing of glycosylated haemoglobin.
  • Patients with type 2 diabetes who are taking a sulphonylurea are at risk of hypoglycaemia and so have a greater need to SMBG.
  • It is not known what the ideal frequency of self-monitoring should be in type 2 diabetes. Current recommendations are based on consensus opinion.


Document references
  1. Diabetes UK; Care recommendations - Self-monitoring of blood glucose
  2. Type 2 diabetes - the management of type 2 diabetes (partial update), NICE Clinical Guideline (May 2009); Type 2 diabetes - newer agents for blood glucose control in type 2 diabetes
  3. When and how should patients with diabetes mellitus test blood glucose? MeReC Bulletin, Volume 13, N0 1, July 2002
  4. Health Technology Assessment; Monitoring blood glucose control in diabetes mellitus: a systematic review. October 2003; Volume 4, number 12.

Internet and further reading Acknowledgements EMIS is grateful to Dr Colin Tidy for writing this article. The final copy has passed scrutiny by the independent Mentor GP reviewing team. ©EMIS 2009.
Document ID: 455
Document Version: 4
Document Reference: bgp25203
Last Updated: 17 Sep 2009
Planned Review: 16 Sep 2012

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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