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Bariatric Surgery

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Bariatric surgical procedures are an option for treating severe obesity, by reducing intake or absorption of calories. There are various procedures, all of which have potential complications. Bariatric surgery should always be performed in a specialist centre, and long-term follow-up of patients is necessary.

For more general information regarding obesity and its management, see our records on:

Obesity in Adults
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Indications1

Bariatric surgery is an option in severely obese patients, where lifestyle/medication have been evaluated but found not to be effective. Surgery can be combined with other treatments. Referrals are usually made via a specialist obesity management service.There are clear guidelines from NICE about who should be considered for bariatric surgery.

Adults

  • BMI ≥40 kg/m2 OR BMI 35-40 kg/m2 with other significant disease (e.g. type 2 diabetes, high blood pressure) that could be improved by weight loss and:
    • All appropriate non-surgical measures have failed to achieve or maintain adequate clinically beneficial weight loss for at least 6 months
    • They are receiving or will receive intensive specialist management
    • They are generally fit for anaesthesia and surgery
    • They commit to the need for long-term follow-up
  • As a first-line option if BMI of >50 kg/m2 and surgical intervention is considered appropriate (and consider orlistat or sibutramine before surgery if the waiting time is long)

Young people
Surgery is not generally recommended as it is fraught with ethical issues and the potential long-term benefits and complications are not yet known.2 However, NICE suggests that it may be considered in exceptional circumstances, if:

  • They have achieved or nearly achieved physiological maturity
  • BMI ≥40 kg/m2 OR 35-40 kg/m2 with other significant disease (e.g. type 2 diabetes, high blood pressure) that could be improved by weight loss
  • All appropriate non-surgical measures have failed to achieve or maintain adequate clinically beneficial weight loss for at least 6 months2
  • They are receiving or will receive intensive specialist management
  • They are fit for anaesthesia and surgery
  • They commit to the need for long-term follow-up

Some research suggests that it may also be worthwhile for those with a BMI 30-35.3 The risk/benefit ratio is less certain for the young, the elderly and those with a BMI >70.4

Contra-indications and cautions3
  • Inability to give informed consent, e.g. immaturity or mental disability.
  • Unfit for surgery.
  • Some centres advise pre-operative psychiatric and nutritionalist assessment.
Types of procedure for bariatric surgery4
  • Procedures are classified as restrictive, malabsorptive or both.
    • Restrictive procedures produce a feeling of fullness with lower food intake.
    • Malabsorptive procedures limit calorie uptake from the intestine.
  • There are various procedures and variations on them. Many can be performed by laparoscopy.
  • The most commonly used procedures are laparoscopic adjustable gastric banding and roux-en-Y gastric bypass.

Bariatric surgery procedures currently used

  • Restrictive
    • Laparoscopic adjustable gastric banding
    • Sleeve gastrectomy
  • Malabsorptive
    • Biliopancreatic diversion with/without duodenal switch
  • Both restrictive and malabsorptive
    • Roux-en-Y gastric bypass
    • Other types of gastric bypass, e.g. mini-gastric bypass
  • Other procedures (considered experimental)
    • Gastric stimulation
    • Intragastric balloon

Choice of procedure1,5

Bariatric surgery should be performed by a specialist team in a tertiary centre. The choice of procedure is partly determined by local expertise; it is important that all operations be performed by an experienced surgeon. Factors to take into account are:

  • Fitness for surgery
  • Degree of obesity
  • Some centres have a 2-stage approach, using a restrictive procedure initially, followed by a malabsorptive procedure later if necessary
  • Tailoring the procedure to the patient may be a way forward.3 One centre allocated choice of procedure according to the patients' eating patterns6

Whilst all the procedures, if successful, result in weight loss, the biliopancreatic diversion with duodenal switch appears to reduce the BMI the most effectively with greater loss of adiposity when compared to a gastric bypass, sleeve gastrectomy and adjustable gastric banding.7 Currently, the increasingly favoured technique is Roux-en-Y gastric bypass in Europe and laparoscopic adjustable gastric banding in the United States.8

Explanation of bariatric procedures3,4

  • Laparoscopic adjustable gastric banding: places a constricting ring around the stomach, below the gastro-oesphageal junction. The bands incorporate an inflatable balloon which can adjust the size of the ring, to regulate food intake.
  • Sleeve gastrectomy:: most of the stomach is removed, leaving a sleeve-shaped cylinder of stomach with reduced capacity. This procedure is irreversible.
  • Gastric bypass creates a small gastric pouch (restrictive) joined to the jejunum, bypassing the duodenum and proximal jejunum (malabsorptive).
  • Biliopancreatic diversion: is a more extensive form of the gastric bypass, with the gastric pouch joined to the ileum. It produces more extreme malabsorption.
  • Duodenal switch: biliopancreatic diversion is sometimes performed with a duodenal switch. This produces a short distal length of small intestine, severely limiting caloric absorption.
  • Jejuno-ileal bypass: is no longer used, having a high morbidity and mortality.
  • Gastric stimulation: uses an implanted pacemaker-type device to produce electrical gastric stimulation.9
  • Intragastric ballon: this is an endoscopic rather than surgical procedure, placing a silicone balloon inflated in the stomach to promote a feeling of satiety. There is insufficient evidence to assess its effectiveness, and there were complications such as gastric erosions and ulcers.10
Follow-up1
  • Regular specialist dietetic review: micronutrients will need monitoring.
  • Patient support groups should be offered.
Benefits of bariatric surgery procedures
  • Weight loss - although this is not guaranteed. Generally, the malabsorptive procedures seem to produce greater weight loss but carry higher risks. In one trial, long-term weight loss averaged 25% with gastric bypass and 14% with gastric banding.11
  • Reduction in co-morbidities related to obesity, such as diabetes.12 Benefits in the longer term (10 years) may be fewer than those seen at earlier follow-up.4
  • Possibly, there are beneficial metabolic effects through altered release of gut hormones; this may be relevant to patients with diabetes.3
  • Recent evidence suggests that nonalcoholic fatty liver disease (including steatosis, steatohepatitis and fibrosis) appears to improve or completely resolve in the majority of patients after bariatric surgery-induced weight loss.13
  • Reduction in mortality: a large RCT over 10 years found that bariatric surgery reduced overall mortality compared to conventional treatment.11 Deaths rates from diabetes, heart disease and cancer are probably reduced, though deaths from some causes increased (see 'Complications' below).14
Complications and disadvantages of surgery4

Pre-operative discussion is important; patients may have unrealistic ideas about the amount of weight they are likely to lose, the need for follow-up and the potential complications.

  • Perioperative complications as for any abdominal surgery: these include venous thrombo-embolism and death. The less radical (such as gastric banding) and the laparoscopic procedures have fewer serious complications.5
  • Possible complications of banding are: band slippage, leakage, infection or migration.3
  • Surgical complications of bypass surgery include: leakage or stenosis of the stoma, GI ulcers or bleeding, small bowel obstruction and hernias.
  • Nausea and vomiting due to over-eating or to stenosis at the surgery site.
  • Dumping syndrome: symptoms are flushing, light-headedness, palpitations, fatigue and diarrhoea; typically triggered by sugar after a Roux-en-Y gastric bypass. It is a neurohormonal reaction. It may help to discourage over-eating.
  • Malnutrition: micronutrient deficiencies are a recognised problem, especially with malabsorptive procedures. Iron, calcium, folate and fat-soluble vitamin deficiencies can occur. Thiamine, B12 and copper deficiencies may cause neurological symptoms and should be remembered. Protein-calorie malnutrition can also occur. Long-term follow-up is important.
  • Another well-recognised metabolic complication is significant hyperoxaluria which can be mitigated to some extent by aggressive fluid intake, oral calcium and citrate supplementation.15
  • Inadequate weight loss and weight regain. The latter is affected by behavioural patterns that can be assessed pre-operatively in order to identify individuals particularly at risk.16
  • One retrospective study found that some causes of mortality such as suicide, were higher after bariatric surgery compared to controls. Overall mortality rates favoured surgery with particular reduction of death from diabetes, heart disease and cancer.14
  • If the original operation fails, revisional surgery should only be undertaken only in specialist centres by surgeons with extensive experience - due to the high complication and increased mortality rate.1


Document references
  1. Obesity, NICE Clinical Guideline (2006); Obesity: the prevention, identification, assessment and management of overweight and obesity in adults and children.
  2. Caniano DA; Ethical issues in pediatric bariatric surgery. Semin Pediatr Surg. 2009 Aug;18(3):186-192. [abstract]
  3. Korenkov M, Sauerland S; Clinical update: bariatric surgery. Lancet. 2007 Dec 15;370(9604):1988-90.
  4. DeMaria EJ; Bariatric surgery for morbid obesity. N Engl J Med. 2007 May 24;356(21):2176-83.
  5. Colquitt J, Clegg A, Loveman E, et al; Surgery for morbid obesity. Cochrane Database Syst Rev. 2005 Oct 19;(4):CD003641. [abstract]
  6. Goergen M, Arapis K, Limgba A, et al; Laparoscopic Roux-en-Y gastric bypass versus laparoscopic vertical banded gastroplasty: results of a 2-year follow-up study. Surg Endosc. 2007 Apr;21(4):659-64. Epub 2006 Dec 16. [abstract]
  7. Strain GW, Gagner M, Pomp A, et al; Comparison of weight loss and body composition changes with four surgical procedures. Surg Obes Relat Dis. 2009 Apr 14. [abstract]
  8. Favretti F, Ashton D, Busetto L, et al; The Gastric Band: First-Choice Procedure for Obesity Surgery. World J Surg. 2009 Jun 24. [abstract]
  9. Abell TL, Minocha A, Abidi N; Looking to the future: electrical stimulation for obesity. Am J Med Sci. 2006 Apr;331(4):226-32. [abstract]
  10. Fernandes M, Atallah AN, Soares BG, et al; Intragastric balloon for obesity. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004931. [abstract]
  11. Sjostrom L, Narbro K, Sjostrom CD, et al; Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med. 2007 Aug 23;357(8):741-52. [abstract]
  12. Buchwald H, Avidor Y, Braunwald E, et al; Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004 Oct 13;292(14):1724-37. [abstract]
  13. Mummadi RR, Kasturi KS, Chennareddygari S et al.; Effect of bariatric surgery on nonalcoholic fatty liver disease: systematic review and meta-analysis. Database of Abstracts of Reviews of Effects (DARE), June 2009.
  14. Adams TD, Gress RE, Smith SC, et al; Long-term mortality after gastric bypass surgery. N Engl J Med. 2007 Aug 23;357(8):753-61. [abstract]
  15. Whitson JM, Stackhouse GB, Stoller ML; Hyperoxaluria after modern bariatric surgery: case series and literature review. Int Urol Nephrol. 2009 Jul 2. [abstract]
  16. Odom J, Zalesin KC, Washington TL, et al; Behavioral Predictors of Weight Regain after Bariatric Surgery. Obes Surg. 2009 Jun 25. [abstract]

Internet and further reading Acknowledgements EMIS is grateful to Dr Olivia Scott for writing this article and to Dr N Hartree for earlier versions. The final copy has passed scrutiny by the independent Mentor GP reviewing team. ©EMIS 2009.
Document ID: 1844
Document Version: 21
Document Reference: bgp25123
Last Updated: 21 Jul 2009
Planned Review: 21 Jul 2011

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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