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Slipped Upper Femoral Epiphysis

Often atraumatic or associated with a minor injury. Slipped upper femoral epiphysis is one of the most common adolescent hip disorders and represents a unique type of instability of the proximal femoral growth plate.1 Four separate clinical groups are seen:

  • Pre-slip: wide epiphyseal line without slippage
  • Acute form: slippage occurs suddenly, normally spontaneously
  • Acute-on-chronic: slippage occurs acutely where there is already existing chronic slip
  • Chronic: steadily progressive slippage (commonest form)
Epidemiology
  • Incidence is 30-60/100,000 children per year.
  • Most commonly occurs in boys of 10-17 years of age. Peak age is 13 years for boys and 11.5 years for girls.
  • It is the commonest hip disorder in adolescents.
  • Left hip is more commonly affected than right; bilateral in 20-40% of cases.2
  • Three times as common in boys.3

Risk factors

  • Mechanical: local trauma, obesity
  • Inflammatory conditions: neglected septic arthritis
  • Hypothyroidism, hypopituitarism, growth hormone deficiency, pseudohypoparathyroidism
  • Previous radiation of the pelvis, chemotherapy, renal osteodystrophy-induced bone dysplasia
Presentation
  • Discomfort in hip, groin, medial thigh or knee (knee pain is referred from hip joint) during walking; pain accentuated by running, jumping, or pivoting activities.
  • Pre-slip: slight discomfort.
  • Acute:
    • Severe pain such that child is unable to walk or stand.
    • Alterations in gait, including limp on affected side, external rotation of leg, and trunk shift.
    • Hip motion limited, especially internal rotation and abduction due to pain.
  • Acute-on-chronic: pain, limp and altered gait occurring for several months suddenly becomes very painful.
  • Chronic:
    • Mild symptoms with child able to walk with altered gait. Significant number of cases report knee pain as only symptom.
    • External rotation of leg during walking. Range of motion of hip shows reduced internal rotation with additional external rotation.
    • When flexed up, hip tends to move in externally rotated position.
    • Mild-to-moderate shortening of affected leg.
    • Atrophy of thigh muscle may be noted.
Differential diagnosis

Other causes of hip pain, e.g.:

Investigations

Anteroposterior and 'frog-leg' lateral X-rays show widening of epiphyseal line or displacement of the femoral head.

  • Earliest findings include globular swelling of the joint capsule, irregular widening of the epiphyseal line and decalcification of the epiphyseal border of the metaphysis.
  • Epiphysis normally extends slightly cephalad to the upper border of the femoral neck.
  • Small amounts of slippage can be detected by the epiphyseal edge, becoming flush with the superior border of the neck.
  • Sometimes, however, the only evidence of epiphyseal injury is slight widening of the growth plate.
Associated diseases
  • Associated injuries are common with slipped capital femoral epiphysis; patients should be evaluated for possible pelvic fractures.
Management
  • Avoid moving or rotating leg. Patient should not be allowed to walk.
  • Provide analgesia and immediate orthopaedic referral if the diagnosis is suspected.
  • Patient should be scheduled for surgery immediately.
  • Surgical closure of the epiphysis usually by inserting screws percutaneously.4
  • Corrective osteotomy is usually reserved for treatment of severe deformities after the patient has stopped growing.2
Complications
  • Chondrolysis (degeneration of the articular cartilage), avascular necrosis of the epiphysis, and long-term effects of altered femoral head anatomy.
  • Chondrolysis is seen in 5-8% of slips, and is associated with specific risk factors: African-American race, female gender, screw penetration of articular cartilage, body cast immobilisation, femoral neck osteotomy, and severe slips.
  • Avascular necrosis of the epiphysis5 occurs in 10-25% of cases, and is associated with attempts to reduce a displaced epiphysis before treatment and with osteotomy of the femoral neck.
Prognosis
  • Prognosis depends on initial degree of epiphyseal slippage.
  • End result is good to excellent in 94-96% of cases if fragments are displaced by less than one-third of the diameter of the femoral neck.
  • With increasing displacement, complications increase and up to 45% of patients have a fair-to-poor surgical result.


Document references
  1. Marano H, Lin D; Slipped Capital Femoral Epiphysis. eMedicine, June 2006.
  2. Loder RT; Slipped capital femoral epiphysis. Am Fam Physician. 1998 May 1;57(9):2135-42, 2148-50. [abstract]
  3. Lehmann CL, Arons RR, Loder RT, et al; The epidemiology of slipped capital femoral epiphysis: an update. J Pediatr Orthop. 2006 May-Jun;26(3):286-90. [abstract]
  4. Kenny P, Higgins T, Sedhom M, et al; Slipped upper femoral epiphysis. A retrospective, clinical and radiological study of fixation with a single screw. J Pediatr Orthop B. 2003 Mar;12(2):97-9. [abstract]
  5. Tokmakova KP, Stanton RP, Mason DE; Factors influencing the development of osteonecrosis in patients treated for slipped capital femoral epiphysis. J Bone Joint Surg Am. 2003 May;85-A(5):798-801. [abstract]

Internet and further reading Acknowledgements EMIS is grateful to Dr Colin Tidy for writing this article. The final copy has passed scrutiny by the independent Mentor GP reviewing team. ©EMIS 2008.
DocID: 958
Document Version: 21
DocRef: bgp1091
Last Updated: 27 Jun 2008
Review Date: 27 Jun 2010
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