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Abdominal Pain in Childhood

Childhood abdominal pain is a very common reason for parents to seek medical advice. The good news is that most childhood abdominal pain is benign and self-limiting, resolving rapidly. However, this means that we need to be especially astute at picking up the more serious cases which can even be life-threatening.

Pathological causes of abdominal pain1
  1. Visceral pain (splanchnic) e.g. stomach, intestine
  2. Parietal pain (somatic) - from parietal peritoneum
  3. Referred pain e.g. pneumonia

Visceral pain is usually dull whilst parietal and referred pain is usually sharp and discrete.

Presentation

History

This varies according to the age of patient.

  • Neonates and babies may present with crying and difficulty feeding
  • Toddlers - can usually answer simple questions
  • Teenagers - may be more embarrassed to talk about the pain
  • Ask about duration, location, character
  • Associated symptoms include vomiting, diarrhoea, recent travel, fever, groin pain, urine symptoms, bloody diarrhoea, vaginal discharge
  • Gynaecological and sexual history may also be appropriate

Physical examination

  • Does the child look ill?
  • Babies may have abnormal facial expressions
  • Haemodynamic status - pulse rate, blood pressure in older patients, mucous membranes, urine e.g. wet nappy
  • Rash e.g. Henoch Schonlein purpura
  • Icteric
  • Temperature
  • Can you distract the child from the pain
  • Ask patient to blow stomach all the way in and out
  • Get them to point at the pain with one finger
  • Check the abdomen for tenderness, rebound tenderness, guarding, organomegaly, loin pain, bowel sounds
  • In males check testes for torsion
  • Rectal and vaginal examinations should only be performed if will provide significant information
  • Other system examination as appropriate
  • Urine dipstick

Chronic Abdominal Pain - Alarm Symptoms2

  • Unintentional weight loss
  • Growth failure or slowing
  • Unexplained fever
  • Chronic severe diarrhoea or significant vomiting
  • Gastrointestinal bleeding
  • Family history of Inflammatory Bowel Disease
  • Persistent chronic RIF or RUQ pain

Causes
Causes of Abdominal Pain in Children
1
 
Emergencies/life-threatening
Other causes
Medical causes
Diabetic Ketoacidosis
Inflammatory bowel disease
Acute adrenal failure
Gastroenteritis (bacteria or viruses)
Constipation
Flatulence
Mesenteric lymphadenitis
Peptic ulcer disease
Urinary tract infection
Ureteric calculi
Hepatitis
Cholecystitis
Pancreatitis
Sickle cell anaemia/crises
Henoch Schonlein purpura
Surgical causes
Appendicitis
Bowel obstruction (e.g. intussusception, volvulus)
Trauma
Incarcerated hernia
Peritonitis
Testicular torsion
 
Gynaecological causes
  Dysmenorrhoea
Mittelschmerz
Pelvic inflammatory disease
Endometriosis
Obstetric causes
Ectopic pregnancy
Ovarian cyst rupture/torsion
Abortion
 
Drugs/Toxins
Paracetamol overdose
Iron overdose
Venoms
Soap ingestion
Erythromycin
Referred pain
  Pneumonia
Rare causes
  Angioneurotic oedema
Familial Mediterranean fever
Unknown aetiology
  Infantile colic
Functional bowel disease
Investigations
  • These will depend upon the clinical findings and may not be needed e.g. viral gastroenteritis
  • Urinalysis - microscopy, culture, sensitivities, stone analysis
  • Blood tests - capillary blood glucose, plasma glucose, full blood count, renal function, liver function, inflammatory markers, amylase
  • Other blood tests if indicated e.g. paracetamol levels, thyroid function tests
  • Stool samples if diarrhoea - microscopy, culture, sensitivity, ova, cysts, parasites
  • Abdominal imaging - abdominal X-ray (looking for obstruction), chest X-ray (looking for pneumonia and air under diaphragm), ultrasound scan of the abdomen and testes
  • CT scan may also be appropriate
  • More specialists investigations e.g. barium enema will depend upon preliminary findings
Differential diagnosis

A good way to consider the differential diagnosis is according to the patients age.

Differential diagnosis of abdominal pain in children according to age
1
Age group
Medical causes
Surgical causes
Other causes
Birth - 1 year
Gastroenteritis
Constipation
UTI
Intussusception
Volvulus
Incarcerated hernia
Infantile colic
Hirschsprung's disease
2 - 5 year
Gastroenteritis
Constipation
UTI
Appendicitis
Intussusception
Volvulus
Trauma
Mesenteric lymphadenitis
Henoch Schonlein purpura
Sickle cell crises
6 - 11 year
Gastroenteritis
Constipation
UTI
Appendicitis
Trauma
Mesenteric lymphadenitis
Henoch Schonlein purpura
Sickle cell crises
Pneumonia
Functional pain
12 - 18 year
Gastroenteritis
Constipation
Appendicitis
Trauma
Ovarian/testicular torsion
Dysmenorrhoea
Mittelschmerz
Threatened abortion
Ectopic pregnancy
Pelvic inflammatory disease
Management

This depends on the cause. Self-limiting causes e.g. gastroenteritis may just require reassurance and simple advice to parents and carers. The advice should include continued use of the child's usual and age apropriate diet to prevent and limit dehydration.3 Clear liquids should not be substituted for oral rehydration solutions (ORS) or regular diets to prevent or treat dehydration.3 For other causes more specific therapies may be required e.g. surgery in appendicitis, treatment of diabetic ketoacidosis with insulin, fluids and potassium.

Some specific causes

Infantile colic

  • Synonym: gripe
  • Occurs in babies in first few months after birth month
  • Babies scream, draw up their knees and experience severe pain
  • Episodes can last up to 3 hours and occur often in a week
  • Changes in feed type and routine may help
  • Over the counter medicines e.g. simethicone may help, but have not been proven to be of benefit4

Mesenteric lymphadenitis

  • This is associated with adenoviral infection
  • Presents similar to appendicitis but there is no peritonism
  • The abdominal pain tends to be more diffuse
  • There may also be generalised lymphadenopathy

Functional abdominal pain5

  • Consider it in patients with abdominal pain on and off for three months but with otherwise normal investigations
  • There is no clear cause but enhanced sensitivity of the enteric nervous system and stress6 probably play a role
  • H. pylori infection has not been shown to be a cause7
  • It can affect 15% of school age children
  • Management involves reassurance and supportive therapy e.g. muscle relaxants, antacids
  • Crucially management involves education of patient and carers to prevent the abdominal pain taking over their lives. An example of this is not allowing the abdominal pain be a reason to take time off school.
  • Other factors that may help is a good nights sleep, a healthy diet and reduced stress levels8
  • The prognosis is good and the condition remits spontaneously

Pitfalls to watch out for in children with abdominal pain
  • In females always consider gynaecological disorders and pregnancy related disorders (you may need to speak to the patient alone)
  • Male patients - always consider torsion of the testes
  • Consider illicit drug use
  • Is there a possibility of child abuse?
  • Refer patient if you are unsure or concerned
  • Repeat physical examination may help
  • Use analgesia as required - it does not affect diagnostic accuracy


Document References
  1. Lake AM; Chronic abdominal pain in childhood: diagnosis and management. Am Fam Physician. 1999 Apr 1;59(7):1823-30. [abstract]
  2. Berger MY, Gieteling MJ, Benninga MA; Chronic abdominal pain in children. BMJ. 2007 May 12;334(7601):997-1002.
  3. King CK, Glass R, Bresee JS, et al; Managing acute gastroenteritis among children: oral rehydration, maintenance, and nutritional therapy. MMWR Recomm Rep. 2003 Nov 21;52(RR-16):1-16. [abstract]
  4. Rogovik AL, Goldman RD; Treating infants' colic. Can Fam Physician. 2005 Sep;51:1209-11. [abstract]
  5. No authors listed; Chronic abdominal pain in children. Pediatrics. 2005 Mar;115(3):e370-81. [abstract]
  6. Kaminsky L, Robertson M, Dewey D; Psychological correlates of depression in children with recurrent abdominal pain. J Pediatr Psychol. 2006 Oct;31(9):956-66. Epub 2006 Mar 2. [abstract]
  7. Lin MH, Chen LK, Hwang SJ, et al; Childhood functional abdominal pain and Helicobacter pylori infection. Hepatogastroenterology. 2006 Nov-Dec;53(72):883-6. [abstract]
  8. Rasquin-Weber A, Hyman PE, Cucchiara S, et al; Childhood functional gastrointestinal disorders. Gut. 1999 Sep;45 Suppl 2:II60-8. [abstract]
Acknowledgements EMIS is grateful to Dr Gurvinder Rull for writing this article. The final copy has passed scrutiny by the independent Mentor GP reviewing team. ©EMIS 2007.
DocID: 1736
Document Version: 21
DocRef: bgp523
Last Updated: 14 May 2007
Review Date: 13 May 2009






















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