Bupropion

About bupropion

Stopping smoking in somebody who smokes regularly causes a reduction of certain chemicals in the brain, which leads to cravings, anxiety, irritability and other symptoms associated with 'giving up'. Bupropion increases the levels of these chemicals, reducing cravings and withdrawal symptoms.

Before taking bupropion

Before taking bupropion make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you suffer from liver or kidney problems
• If you suffer from epilepsy or any other condition which causes seizures (fits)
• If you have ever suffered from an eating disorder, such as anorexia nervosa or bulimia
• If you have a tumour in your brain, spine or nervous system
• If you have ever had a serious head injury
• If you suffer from a bipolar disorder
• If you are an alcoholic or are suffering from withdrawal symptoms from alcohol or drugs
• If you suffer from diabetes
• If you suffer from psoriasis
• If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines

How to take bupropion

• Always read the manufacturer's information leaflet, if possible, before beginning treatment.
• Take Bupropion exactly as directed by your doctor.
• Bupropion tablets should be swallowed whole, not crushed or chewed, with a glass of water.
• Leave at least 8 hours between doses.
• Start taking Bupropion 1 to 2 weeks before your target stop date. If you are still smoking after 7 weeks speak to your doctor.
• Bupropion is not recommended in people under 18 years old.
• Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of Bupropion contact your doctor or go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if it is empty.
• This medicine is for you. Never give it to others, even if their condition appears to be the same as yours.

Getting the most from your treatment

• Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside Bupropion.
• Keep your regular appointments with your doctor. Your blood pressure may need to be measured while taking this medicine.
• Bupropion will help you to give up smoking but you will also need to use will power.
• Bupropion may cause problems with eyesight and dizziness. Make sure that your reactions are normal before driving, operating machinery or doing other jobs that could be dangerous if you couldn't see properly or became dizzy.

Can bupropion cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Other side effects include tummy upset, difficulty sleeping, shakiness, problems concentrating, dizziness, disturbance of taste, depression, agitation, worry, skin rashes, itching, sweating or fever (high temperature), chest pain, weakness, fast heartbeat, flushing, loss of appetite, buzzing in the ears, problems with eyesight, strange dreams, memory problems, pins and needles, poor co-ordination, seeing or hearing things that aren't real.

Bupropion can increase the risk of seizures (fits) in some people who already have a higher risk than the general population. Your doctor will be able to discuss this with you if you are concerned.

Important: Depression can occur as a symptom of nicotine withdrawl. Suicidal thoughts and behaviour have been associated with bupropion treatment soon after stopping smoking. Tell your doctor straight away if you are having thoughts of harming yourself.

How to store bupropion

• Keep all medicines out of the reach of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines