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Pancreatin
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About pancreatin
| Type of medicine | Pancreatic enzyme |
| Used for | Cystic fibrosis After removal of the pancreas by surgery Chronic pancreatitis (long-term inflammation of the pancreas) |
| Also called | Nutrizym® 10 Pancrex® Pancrex® V Pancrex® V Forte Creon® Micro Creon® 10 000 Higher strength preparations: |
| Available as | Tablets, capsules, granules and powder |
Pancreatin is a combination of pancreatic enzymes that are normally produced naturally in the body. They help to digest fat, starch and protein in the food you eat. Pancreatin is given to people who do not produce enough enzymes to digest their food properly, such as those suffering from cystic fibrosis, problems with the pancreas, or in those who have had their pancreas removed. The higher-strength preparations are not suitable for children aged 15 years or under with cystic fibrosis.
Before taking pancreatin
Before taking pancreatin make sure your doctor or pharmacist knows:
- If you are allergic to pork or other pig products.
- If you are pregnant, trying for a baby or breast-feeding.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take pancreatin
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take pancreatin exactly as directed by your doctor. Your doctor will tell you how much to take and may adjust your dose from time to time to make sure it continues to be the right dose for you.
- Pancreatin should always be taken either with food or immediately before or after every meal or snack.
- Pancreatin granules or powder can be swallowed with a drink of water but it is important that you do not chew the granules or powder. They can also be mixed with liquids or sprinkled on soft food, then swallowed immediately without chewing.
- Pancreatin capsules can be swallowed whole or opened up and the contents mixed with soft food and then swallowed immediately. Do not chew the capsules or the contents.
- Pancreatin tablets should be swallowed whole before each snack or meal.
- Do not mix pancreatin with hot food or liquids. Heat will stop pancreatin working properly.
- Drink plenty of water while you are being treated with pancreatin.
Getting the most from your treatment
- Do not take indigestion remedies at the same time as pancreatin. If you need to take an indigestion remedy such as an antacid, take it at least two hours before or two hours after a dose of pancreatin.
- If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
- Keep your regular doctor's appointment so your progress can be monitored.
- Do not stop taking this medicine without speaking to your doctor first.
- If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
Can pancreatin cause problems?
Along with their useful effects all medicines can cause unwanted side-effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Feeling or being sick, diarrhoea, abdominal pain | Discuss this with your doctor as the dose you are taking may need adjusting. Let your doctor know straight away if, after taking pancreatin for some time, you develop any new or severe symptoms |
| Irritation of the mouth or back passage | Discuss this with your doctor as the dose you are taking may need adjusting |
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store pancreatin
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Creon® Micro, Solvay Healthcare Limited, electronic Medicines Compendium. Dated July 2004, accessed July 2009
- Manufacturer's PIL, Creon® 10000, Solvay Healthcare Limited, electronic Medicines Compendium. Dated August 2008, accessed July 2009
- Manufacturer's PIL, Pancrease® HL Capsules, Janssen-Cilag Ltd, electronic Medicines Compendium. Dated April 2008, accessed July 2009.
- British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
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The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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