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Memantine
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About memantine
| Type of medicine | Anti-dementia drugs (glutamatergic modulator) |
| Used for | Alzheimer's disease |
| Also called | Ebixa® |
| Available as | Tablets and oral drops |
Memantine is used to treat Alzheimer's disease. It cannot cure Alzheimer's disease but it may help with memory loss. It works by blocking the effect of a chemical in the brain that is thought to cause memory disturbances.
Before taking memantine
Before taking memantine make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from liver, kidney or heart problems.
- If you suffer from epilepsy or have ever had convulsions.
- If you have a history of high and uncontrolled blood pressure.
- If you have an infection of the bladder or urinary tract.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take memantine
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Your caregiver will help you take your medication exactly as directed by your doctor.
- When starting your treatment your doctor will start off with a small dose and gradually increase the dose. This allows your doctor to make sure that you have the right dose that helps your condition and avoids any unwanted symptoms.
- Take memantine at the same time each day and try to avoid missing any doses. It can be taken with or without food.
- If you miss a dose take it a soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the usual time. Never take two doses together to make up.
Getting the most from your treatment
- It may take several weeks before memantine appears to take effect. You should not stop taking your medication unless directed to do so by your doctor.
- Keep your regular doctor or clinic appointments so your progress can be assessed.
- Changes in diet particularly a change from a mixed diet that includes meat and vegetables, to a vegetarian diet may have an effect on treatment with memantine. Talk to your doctor before you make any major changes to your diet.
- Discuss with your doctor if your illness will allow you to still drive or operate machinery safely.
- While taking memantine you must avoid getting pregnant. Ask your doctor or pharmacist about suitable contraception if this is relevant to you.
Can memantine cause problems
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Constipation | Try to eat a well balanced diet containing plenty of fibre and drink 6-8 glasses of water each day. If constipation continues to be a problem speak to your pharmacist or doctor. |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If headache continues speak with your doctor. |
| Dizziness and/or drowsiness | Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Avoid alcohol; it will increase any feelings of drowsiness |
| Confusion or tiredness | If you experience these side effects speak with your doctor although they may be as a result of your conditions as well as the medicines you are taking. |
| Hallucinations and/or fits | If you experience these side effects speak with your doctor as soon as possible. |
How to store memantine
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Ebixa® 10 mg Film-Coated Tablets, Lundbeck Limited, electronic Medicines Compendium. Revised May 2008, accessed September 2008.
- Manufacturer's PIL, Ebixa® 10 mg/g Oral Drops, Lundbeck Limited, electronic Medicines Compendium. Revised May 2008, accessed September 2008.
- British National Formulary; 56th Edition (September 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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