Zafirlukast

About zafirlukast

Certain agents or activities are commonly associated with the onset of an asthma attack and these are often referred to as trigger factors. Exposure to these factors can cause the body to produce substances called leukotrienes that cause inflammation and tightening of the airways during an asthma attack. Zafirlukast works by blocking the effects of leukotrienes.

Zafirlukast is used in mild to moderate asthma to control symptoms and prevent it from getting worse. It may also be of benefit in chest tightness, experienced by patients with asthma during exercise.

Before taking zafirlukast

Before taking zafirlukast make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you suffer from liver or kidney problems.
• If you smoke (this may affect the dose you need).
• If you are taking any other medicines, including those available to buy without a prescription, herbal or complementary medicines.

• Zafirlukast is not recommended in children under 12 years.

How to take zafirlukast

• Take your medication exactly as directed by your doctor.
• Each dose of zafirlukast should be taken on an empty stomach and not with a meal.
• Try to take each dose at the same times each day to avoid missing a dose. If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next dose, take this as usual, missing out the dose you forgot. Do not take two doses at the same time.

Getting the most from your treatment

• Zafirlukast takes time to work in the body. It will not bring rapid relief in sudden asthma attacks and should not be used in this way. Your doctor should provide you with another medication for this purpose.
• Keep your regular appointments with your doctor so your progress can be monitored.
• Do not stop taking zafirlukast without speaking to your doctor first. You should continue to take zafirlukast even when you are not experiencing any problems with your asthma.
• If your asthma gets worse you should see your doctor as soon as possible.

Can zafirlukast cause problems

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Other side-effects may include a feeling of discomfort, stomach pain, chest infections, sleeplessness, pain in the joints or muscles, loss of appetite, itching, tiredness, lack of energy or flu-like symptoms. If you experience these or any other worrying symptoms, which you think may be due to this medicine, discuss them with your doctor or pharmacist.

Important: If you experience a persistent feeling of sickness or persistent vomiting, if you generally feel unwell, experience jaundice (yellowing of the skin and whites of the eyes) or have a pain on the right side of your stomach just below your ribs, you should contact your doctor immediately.

Important: If you experience any swelling or water retention, or a skin rash and itching, stop taking zafirlukast and contact your doctor immediately.

Important: If you start to bruise easily or experience any unusual bleeding, including heavy menstrual periods, a persistent fever or sore throat, contact your doctor immediately.

Important: If you develop a combination of the following symptoms, severe sinusitis, increasing breathlessness, flu-like symptoms, skin rash, tummy pain, numbness or pins and needles in the arms or legs, tell your doctor immediately.

How to store zafirlukast

• Keep all medicines out of the reach of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines