Tretinoin (topical)
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About tretinoin (topical)
| Type of medicine | Retinoid |
| Used for | Mild to moderate acne |
| Also called | Retin-A® Aknemycin® Plus (tretinoin with erythromycin) |
| Available as | Gel (Retin-A®) Solution (Aknemycin® Plus) |
About tretinoin (topical)
Tretinoin works by reducing the production of sebum, the oily substance produced by the skin. Sebum can block pores leading to spots, blackheads and inflammation.
Before using tretinoin (topical)
Before using tretinoin topical make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from eczema or a condition causing inflammation of the skin.
- If you, or a family member, have suffered from cutaneous epithelioma (a type of skin cancer).
- If you have ever had an allergic reaction to this or any other medicine.
How to use tretinoin (topical)
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Use this medication exactly as directed by your doctor. It is for for external use only.
- Apply tretinoin as a thin layer to the affected area after washing and drying your skin.
- Avoid any contact with the eyes, mouth, and mucous membranes (eg linings of the nose).
- Try not to let tretinoin build up in the folds or creases of your skin.
Getting the most from your treatment
- It can take as long as 6 - 8 weeks for an improvement to be seen.
- Do not use on sunburnt or broken skin. Allow any peeling to heal before using tretinoin.
- Avoid sunbeds and wear protective clothing in direct sunlight, or use a sun-cream higher than factor 15.
- Avoid the use of exfoliating cosmetics; if your skin is peeling as a result of this or another type of product, let your skin recover before using tretinoin.
- Women should use effective contraception - the progestogen only pill is not effective while using tretinoin. Ask your doctor or pharmacist for advice.
Can tretinoin (topical) cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects | What can I do if I experience this |
| Stinging, burning or irritation, itching, redness and peeling | Try missing a few doses to see if this lessens. If it is severe or troublesome, speak with your doctor |
| Change in skin colour | This should disappear when you stop using tretinoin |
If you experience any other symptoms which you think may be due to this preparation, speak with your doctor or pharmacist.
How to store tretinoin (topical)
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- British National Formulary; 54th Edition (September 2007) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
- Manufacturer's PIL, Retin-A®, Janssen-Cilag Limited, electronic Medicines Compendium. Text approved December 2007, accessed 12 March 2008.
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest.
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