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Deferiprone

  • Deferiprone may give your urine a reddish-brown colour but this is nothing to worry about.
  • If you develop unexplained flu-like symptoms or a sore throat, see a doctor straight away.

About deferiprone

Type of medicineIron chelating agent
Used forIron overload in thalassaemia major
Also calledFerriprox®
Available asTablets, oral solution

Deferiprone is used to treat conditions where there is too much iron present in the body. It works by combining with iron to form a complex that the body can remove and this reduces the level of iron in the body. It is especially useful in patients suffering from a blood disorder called thalassaemia, in which accumulation of iron can be a problem.

Before taking deferiprone

Before taking deferiprone make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from liver or kidney problems.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take deferiprone

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take your medication exactly as your doctor has directed.
  • Try to take deferiprone at the same times each day to avoid missing any doses.
  • If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.

Getting the most from your treatment

  • Deferiprone may colour your urine red/brown. This is completely harmless and there is no need for it to be a cause for concern.
  • If you are a woman it is important that you do not become pregnant while taking deferiprone. Ask your doctor or pharmacist for advice about suitable contraception.
  • Do not take aluminium-containing antacids at the same time as deferiprone. Your pharmacist can give you advice about suitable alternatives.
  • Keep your regular doctor's appointment so your progress can be monitored.
  • Do not stop taking this medicine without speaking to your doctor first.
  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

Can deferiprone cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
Feeling or being sick, abdominal painEat little and often and stick to simple foods
DiarrhoeaDrink plenty of water to replace any lost fluids
Joint painIf troublesome, speak with your doctor

Important: If you develop an unexplained fever, flu-like symptoms or a sore throat, speak with your doctor immediately or go to your local accident and emergency department without delay.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store deferiprone

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 55th Edition (March 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008DocID:
3722
DocRef:
dils3710
Last Reviewed:
17 Nov 2008
Version:
22
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