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Topiramate
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About topiramate
| Type of medicine | Antiepileptic |
| Used for | Treatment of epilepsy Prevention of migraine |
| Also called | Topamax Topamax Sprinkle |
| Available as | Tablets Sprinkle Capsules |
Topiramate is used alongside other antiepileptics to control the convulsions (fits or seizures) in some forms of epilepsy by reducing the activity in the brain. It can also be used on its own in patients over 6 years old who have been newly diagnosed with epilepsy.
Topiramate is also used by specialists to help prevent migraines.
Before taking topiramate
Before taking topiramate make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have liver or kidney problems
- If you have ever had kidney stones or have been told you have high levels of calcium in your urine
- If you have porphyria (a blood disorder)
- If you have a history of depression
How to take topiramate
- Take topiramate exactly as directed by your doctor.
- Always read the manufacturer's information leaflet, if possible, before beginning treatment.
- Topiramate capsules can be swallowed whole with a glass of water or they can be opened and the contents sprinkled onto soft food, such as yoghurt, before eating.
- Do not stop taking topiramate without speaking to your doctor first. Your doctor will need to reduce the dose you are taking gradually.
Getting the most from your treatment
- Try to drink plenty of water while you are taking topiramate, especially if you work in a hot environment.
- Avoid drinking alcohol while you are taking topiramate. Alcohol can increase any feelings of drowsiness or dizziness.
- Topiramate may reduce the effectiveness of the contraceptive pill. Speak to your doctor about contraception.
- You may have to change your pill or use another method of contraception such as condoms.
- While you are taking topiramate, there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, tell your doctor straight away.
Can topiramate cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Nausea | Eat little and often. Stick to simple foods such as dry toast. |
| Dizziness, drowsiness | Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Avoid alcohol; it will increase any feelings of drowsiness |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If headache continues speak with your doctor. |
| Weight loss | If you are losing a lot of weight speak to your doctor, they may give you a supplement. |
| Dry mouth | Try chewing sugar-free gum, sucking pieces of ice or sugar-free sweets. If this becomes troublesome speak to your pharmacist or doctor. |
Other side effects are pins and needles, problems sleeping and problems concentrating.
Important: If you experience any problems with eyesight or pain in the eyes make an appointment to see your doctor as soon as possible.
How to store topiramate
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest.
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