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Pantoprazole

  • Pantoprazole reduces the amount of acid produced in the stomach.
  • Swallow pantoprazole tablets whole with a drink of water.
  • Take your doses an hour before a meal.

About pantoprazole

Type of medicineProton pump inhibitor
Used forGastric ulcers, duodenal ulcers, gastro-oesophageal reflux disease and Zollinger-Ellison syndrome
Eradication of Helicobacter pylori
To treat or prevent ulcers caused by non-steroidal anti-inflammatory drugs (NSAIDs)
Available asTablets and injection

Pantoprazole is used to treat certain conditions caused by too much acid being produced in the stomach.

Acid is produced naturally in your stomach to help you digest food and to kill bacteria. This acid is irritant so your body produces a natural mucous barrier which protects the lining of your stomach. In some people this barrier may have broken down allowing the acid to damage the stomach, causing inflammation, ulcers and other conditions. In other people there may be a problem with the muscular band at the top of the stomach that keeps the stomach tightly closed. This may allow the acid to escape and irritate the oesophagus. This is called 'acid reflux' and can cause heartburn and/or oesophagitis.

Proton pump inhibitors such as pantoprazole stop cells in the lining of the stomach from producing too much acid. This can help prevent ulcers from forming or assist the healing process. By decreasing the amount of acid, they can also help to reduce acid reflux related symptoms such as heartburn.

Pantoprazole can also be used to treat irritation and ulceration of the stomach caused by non-steroidal anti-inflammatory drugs (NSAIDs). It can also be used as one part of a treatment to get rid of Helicobacter pylori, a bacterium found in the stomach, which can cause ulcers.

Before taking pantoprazole

Before taking pantoprazole make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have liver or kidney problems.
  • If you have any of the following symptoms: bleeding, difficulty swallowing, being sick frequently, or unexplained weight loss.
  • If you have ever had an allergic reaction to this or to any other medicine.
  • If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines.

How to take pantoprazole

  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take pantoprazole exactly as your doctor has told you.
  • Try to take pantoprazole at the same time each day to avoid missing any doses. The usual dose is once a day in the morning. However, if you are taking pantoprazole for Helicobacter pylori eradication, you will be asked to take two doses a day - one in the morning and one in the evening.
  • Swallow pantoprazole tablets whole. Do not chew or crush the tablets.
  • Take each dose an hour before a meal.
  • If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Getting the most from your treatment

  • Smoking increases the amount of acid produced by the stomach and will aggravate your condition. If you smoke, talk to your doctor or pharmacist about quitting.
  • Try to avoid foods and drinks that may upset your stomach, such as alcohol, citrus fruits/juices, drinks containing caffeine, tomatoes and spicy food.
  • Try to keep your regular appointments with your doctor. This is so your progress can be monitored.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking pantoprazole.
  • If you buy any medicines, check with a pharmacist that they are safe to take with pantoprazole.

Can pantoprazole cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Side-effects - these are uncommon and affect less than 1 in 100 people who take this medicineWhat can I do if I experience this?
Feeling or being sick, stomach ache, flatulenceEat little and often. Stick to simple or bland foods
DiarrhoeaDrink plenty of water to replace any lost fluids. If this continues or is severe, let your doctor know
ConstipationTry to eat a well-balanced diet containing plenty of fibre and drink 6-8 glasses of water each day
HeadacheAsk your pharmacist to recommend a suitable painkiller. If the headache continues speak with your doctor
Dizziness, tirednessMake sure your reactions are normal before you drive or use machines
Dry mouth, itchy rashIf any of these become troublesome, let your doctor know

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store pantoprazole

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

  • Never take more than the prescribed dose. If you suspect that you have taken, or someone else has taken, an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

Comprehensive patient resources are available at www.patient.co.uk


© EMIS 2011 - Author: Helen Allen - Reviewer: Dr Cathy Jackson - Document ID: 3685 - Version: 24 - Reviewed: 19 Oct 2011

For the planned review period see the Data Creation and Quality Control Process.
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