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  • Use penciclovir cream every 2 hours during the day for four days.
  • To avoid spreading the infection, wash your hands before and after applying. Remember infection can also spread to others.
  • This cream is for you. Do not share it with others even if their symptoms are the same as yours.

About penciclovir

Type of medicine Antiviral
Used for Cold sores
Also called Vectavir®
Available as Cream

Penciclovir is an antiviral agent. It works by attacking the herpes simplex virus that causes the infection.

Before using penciclovir

Before using penciclovir make sure your doctor, dentist or pharmacist knows:

  • If you are pregnant.
  • If your immune system is not working properly (for instance if you have AIDS).
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • This cream is not suitable for children under 12 years of age.

How to apply penciclovir

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Use penciclovir exactly as directed by your doctor or dentist.
  • Wash and dry your hands thoroughly before and after handling penciclovir to prevent spreading any infection.
  • Apply penciclovir cream every two hours whilst you are awake. Start using it at the first signs of an attack (for instance, tingling, pain, burning or blisters) and continue using it for 4 days.
  • If you forget a dose, apply it as soon as you remember and then continue using it at the usual times.

Getting the most from your treatment

  • Keep the areas affected by the cold sore as clean and dry as possible.
  • Apply penciclovir for 4 days, otherwise your infection may come back.
  • Avoid contact with the eyes. If any of this preparation gets into your eyes, rinse it off with warm water.
  • Avoid contact with mucous membranes (inside the nose or mouth).
  • If you regularly develop cold sores, or if they develop in your mouth, speak to your doctor as other preparations may be more suitable for you to use.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking or using.

Can penciclovir cause problems?

Along with their useful effects all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who use this medicine What can I do if I experience this
Mild stinging, itching, burning or numbness If troublesome, speak with your doctor or pharmacist

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store penciclovir

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2009 DocID: 3684 DocRef: dils3526 Last Reviewed: 12 May 2009 Version: 22

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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