Colistin

  • Colistin tablets and oral liquid are used to remove bacteria from the bowel before surgery.
  • Inhaled colistin is used to treat chest infections in people with cystic fibrosis.
  • Colistin injection is used to treat bacterial infections which other antibiotics are not be able to treat.

About colistin

Type of medicinePolymyxin antibiotic
Used forRemoving bacteria from the bowel before surgery
Chest infections associated with cystic fibrosis
Bacterial infections which other antibiotics are not be able to treat
Also calledColistimethate sodium
Colomycin®
Promixin®
Available asTablets, oral liquid, nebuliser solution (to be inhaled), and injection

Colistin works by killing the bacteria causing the infection.

Before taking colistin

Before taking colistin make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have kidney problems.
  • If you have myasthenia gravis (a muscle weakening disease) or porphyria (a rare blood disorder).
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take colistin

  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Take colistin exactly as your doctor has told you. If you are using colistin by inhalation, your doctor or nurse will show you how to do this.
  • Space your doses evenly throughout the day. It is important to complete the course unless you are told to stop.
  • Try not to miss any doses. If you do forget a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Getting the most from your treatment

  • Keep your regular appointments with your doctor so your progress can be monitored.
  • If you are using oral combined hormonal contraception (the 'pill'), additional contraceptive precautions such as condoms are not required during a course of this antibiotic unless you are taking the tablets or oral liquid and are sick or have diarrhoea. If you need further advice, speak with your doctor or pharmacist.

Can colistin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. If you experience any of the following side-effects, discuss them with your doctor.

Side-effectsWhat can I do if I experience this
Dizziness, confusion, headache, eyesight problems, vertigo (sensation of spinning), a tingling feeling in the hands, feet or around the mouth, slurred speech, and skin rashIf you experience any of these, discuss them with your doctor
If you are using colistin inhalation: sore throat, chest tightness, breathlessness, and coughLet your doctor know about any of these

If you experience any other symptoms, which you think may be due to this medicine, discuss them with your doctor or pharmacist.

How to store colistin

  • Keep all medicines out of the reach and sight of children
  • Store in a cool, dry place, away from direct heat and light

Important information about all medicines


  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2011DocID: 3618DocRef: dils3209Last Reviewed: 11 Apr 2011Version: 23
For the planned review period see the Data Creation and Quality Control Process.
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