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Lithium

  • The amount of lithium your body will need varies with time and the dose is decided using your blood level. Your doctor will therefore want you to have regular blood tests. The time between blood tests will be closer together at first and get longer once your dose is set.
  • It may take several weeks before you feel the full benefits of this treatment, although lots of people do notice a difference earlier.
  • If you experience blurred vision, loss of appetite, being sick, diarrhoea, muscle weakness, drowsiness, feeling of being slow, shakiness and lack of co-ordination, fainting, inability to urinate (pass water), slurred speech or convulsions (fits) you may have too much lithium in your blood and you should seek urgent medical attention.

About lithium

Type of medicine Mood stabiliser
Used for Manic depression, recurrent depression, bipolar depression
Also called Camcolit; Liskonum; Priadel; Lithium carbonate; Lithium citrate
Available as Tablets
Oral solution

Lithium alters the way that nerve cells respond to chemicals that are present in the brain. It is known that it is a very effective medicine and has been used for more than 50 years. Lithium causes little interference with normal emotional reactions.
Lithium is used to treat mania (overactive and excitable behaviour), certain types of depression, and a condition known as bipolar disorder (where extreme changes in mood are experienced). Lithium decreases the intensity and frequency of mood swings.

Before taking lithium

Before taking lithium make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from heart problems.
  • If you suffer from kidney problems.
  • If you suffer from psoriasis.
  • If you suffer from Addison's disease.
  • If you suffer from myasthenia gravis (a muscle weakening disease).
  • If you suffer from thyroid problems.

How to take lithium

  • A specialist will start your lithium treatment and take blood samples to make sure they have prescribed the correct dose. Once you have begun treatment, you need to have regular blood tests (sometimes called 'a lithium level', a 'serum lithium level' or a 'plasma lithium level'). When your lithium level has stabilised this type of test will be needed less often. This test is important because it tells the doctor how much lithium is in the bloodstream, checking that your dosage is at the correct level. Blood tests are needed more often in the early stages of treatment or if your dosage has changed.
  • Your pharmacist may supply you with a lithium card that gives instrucions about lithium and has your current dose written on it.
  • Do not crush or chew lithium tablets because this could cause you to absorb too much from them.
  • Important: your pharmacist should supply you with the same brand of lithium each time you receive a new prescription. If the medicine you have been given looks different to usual, speak to your pharmacist before taking any of them. This is because different brands give different blood levels of lithium.
  • Try to get into the habit of taking lithium at the same times each day to avoid missing any doses.
  • Do not stop taking lithium without speaking with your doctor first. Stopping suddenly can cause problems and your doctor will want to reduce the dose you are taking gradually.

Getting the most from your treatment

  • Lots of medicines can cause your level of lithium to rise too high so always check with your pharmacist or doctor before taking any medicines; including pain killers such as ibuprofen available to buy in shops and pharmacies.
  • It may take several weeks before you feel the full benefits of this treatment, although lots of people do notice a difference earlier.
  • You should drink plenty of fluids while you are being treated with lithium.
  • Keep to your usual salt intake and avoid any changes from your regular diet e.g. crash dieting programs. This is because it can change your lithium level. Speak with your doctor before making any changes to your diet.
  • If you have an infection or illness that causes heavy sweating, being sick or diarrhoea, consult your doctor, as this can affect the levels of lithium in your blood.

Can lithium cause problems

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects What can I do if I experience this
Nausea After a few days your body will adjust to your new medicine and this side effect should improve.
Needing to pass water more often than normal If you are affected you may just need to plan ahead a little, for example, is there a toilet that you can easily use when you are at work or going about your daily business? You should still continue to drink plenty of water.
Shakiness Your hands may be a little shaky. If affected avoid tasks that need very fine movements where possible.
Reduced co-ordination If affected avoid tasks that require co-ordination such as driving or operating machinery .

Important: If you experience blurred vision, loss of appetite, being sick, diarrhoea, muscle weakness, drowsiness, feeling of being slow, excessive shakiness, a total lack of co-ordination, fainting, inability to urinate (pass water), slurred speech or convulsions (fits) seek urgent medical attention, you may have too much lithium in your blood

How to store lithium

  • Keep all medicines out of the reach of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Keep all medicines out of the sight and reach of children.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before taking this medicine tell your doctor if you are pregnant, trying for a baby or breast-feeding.
  • Before taking this medicine tell your doctor if you have ever had an allergic reaction after taking any medicine.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if it is empty.
  • If you are having any treatment like an operation or dental treatment tell the person carrying out the treatment which medicines you are taking.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.
© EMIS 2006 DocID:
908
DocRef:
dils2974
Last Updated:
24 Oct 2006
Date of Next Review:
23 Oct 2008
Version:
22

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest.

Find out more about updating.

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