Amiloride and Bumetanide

About amiloride and bumetanide

Amiloride and bumetanide combines the actions of a potassium-sparing diuretic and a loop diuretic. Amiloride and bumetanide works by acting in the kidney to remove excess water from the blood, by causing an increase in the removal of salts such as potassium and sodium.

Before taking amiloride and bumetanide

Before taking amiloride and bumetanide make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
• If you have ever had an allergic reaction to this or any other medicine.
• If you have been told that you have hyperkalaemia (high levels of potassium in your blood).
• If you suffer from kidney or liver problems.
• If you are unable to pass water.
• If your prostate gland is enlarged (men only).
• If you suffer from diabetes mellitus.
• If you suffer from Addison's disease.
• If you are currently taking lithium or an ACE inhibitor.

How to take amiloride and bumetanide

• Before beginning treatment, read the manufacturer's printed information leaflet.
• Take your medication exactly as directed by your doctor.
• Try to take amiloride and bumetanide at the same time each day, preferably in the morning, to avoid missing any doses.
• If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.

Getting the most from your treatment

• If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
• Keep your regular doctor's appointments so your progress can be monitored.
• You will need to have regular blood tests to keep an eye on your kidney function.
• Do not stop taking this medicine without speaking to your doctor first.
• If you buy any medicines, check with a pharmacist that they are safe to take with your medicines.
• Amiloride and bumetanide will make you urinate (pass water) more often, which is why it is preferable to take your dose in the morning so as not to disturb your sleep. If you take more than one dose per day, take the last dose before 6pm in the evening.

Can amiloride and bumetanide cause problems

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

How to store amiloride and bumetanide

• Keep all medicines out of the reach of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines