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Bumetanide
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About bumetanide
| Type of medicine | Loop diuretic |
| Used for | Oedema (water retention) |
| Also called | Burinex® |
| Available as | Tablets, solution and injection |
Bumetanide is used to treat oedema (water retention), caused by conditions such as heart failure. It is sometimes referred to as a water tablet.
If the heart becomes less efficient at pumping blood around the body, fluid leaks out of the blood vessels causing swelling in the tissues of the lungs, feet or ankles. Bumetanide prevents the build up of fluid by increasing the amount of urine produced by the kidneys.
Before taking bumetanide
Before taking bumetanide make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have kidney problems, or are dehydrated.
- If you have prostate or liver problems.
- If you have gout or diabetes.
- If you have Addison's disease (a problem of the adrenal glands) or systemic lupus erythematosus (SLE).
- If you suffer from hypotension (low blood pressure).
- If you have been told you have low levels of sodium (salt) or potassium in your blood, or if you are on a low salt diet.
- If you have been told you have high levels of calcium in your blood.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take bumetanide
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take your medication exactly as directed by your doctor.
- Try to take bumetanide at the same time each day to avoid missing any doses.
- Bumetanide will make you urinate (pass water) more often, so your doctor will usually advise you to take your dose in the morning so as not to disturb your sleep. If you take more than one dose per day, take the last dose before 6 pm in the evening.
- If you miss a dose of bumetanide take it as soon as you remember. However, if it is after 6 pm in the evening, skip the missed dose and continue taking it at the usual times. Do not take two doses at the same time to make up.
Getting the most from your treatment
- Keep your regular doctor's appointment so your progress can be monitored.
- Do not stop taking bumetanide without speaking to your doctor first, even if you feel quite well.
- Diuretics help you to lose water. On occasions you may lose too much and become dehydrated, leaving you feeling thirsty and your skin looking and feeling dry. Let your doctor know if this happens.
- If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
Can bumetanide cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Dry mouth | Try chewing sugar-free gum or sweets |
| Feeling or being sick, stomach ache and cramp, indigestion | Eat little and often and stick to simple foods. Drink water to replace any lost fluids |
| Dizziness or feeling faint especially when getting up from sitting or lying down | Getting up slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few minutes before standing |
| Feeling tired or drowsy | Make sure your reactions are normal before driving, operating machinery, or doing any other jobs that could be dangerous if you were not fully alert |
| Diarrhoea | Drink plenty of water to replace any lost fluids |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If the headache continues, speak with your doctor |
| Muscle cramps, joint pain, tinnitus (ringing in the ears), skin rash, increased sensitivity to sunlight, and dehydration | If troublesome, tell your doctor |
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store bumetanide
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Burinex®, Leo Laboratories Ltd, electronic Medicines Compendium. Revised September 2006, accessed 25 June 2008.
- Manufacturer's PIL, Bumetanide Tablets, Actavis UK Ltd, electronic Medicines Compendium. Revised September 2007, accessed 25 June 2008.
- British National Formulary; 55th Edition (March 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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