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Oxprenolol and cyclopenthiazide

  • Usually taken once daily in the morning.
  • You should not suddenly stop taking this medicine unless your doctor tells you otherwise.
  • Your doctor may want to do a blood test to check your salt levels in your blood.

About oxprenolol and cyclopenthiazide

Type of medicine Combination of a beta-blocker and a diuretic
Used for High blood pressure
Also called Trasidrex
Available as Tablets

Oxprenolol works by causing the heart to beat more slowly and with less force.
Cyclopenthiazide works by decreasing the amount of water in the blood.

Before taking oxprenolol and cyclopenthiazide

Before taking oxprenolol and cyclopenthiazide make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from asthma, chronic obstructive pulmonary disease or any other breathing problems.
  • If you have ever been diagnosed as having increased acid levels in your blood (metabolic acidosis).
  • If you have low levels of certain salts (e.g. sodium, potassium) in your body.
  • If you suffer from Addison's disease (not enough production of natural steroid hormones).
  • If you suffer from phaeochromocytoma.
  • If you suffer from diabetes mellitus.
  • If you have heart problems.
  • If you have liver or kidney problems.
  • If you are on a low sodium (salt) diet
  • If you have a thyroid disorder.
  • If you experience cold hands and feet.
  • If you suffer from gout.
  • If you are due to have an operation soon.

How to take oxprenolol and cyclopenthiazide

  • Usually taken once daily in the morning.

Getting the most from your treatment

  • If you are diabetic, you should carefully monitor your blood sugar.
  • You should not suddenly stop taking this medicine unless your doctor tells you otherwise.
  • Your doctor may want to do a blood test to check your salt levels in your blood.

Can oxprenolol and cyclopenthiazide cause problems

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicine What can I do if I experience this
Slow heart rate, tiredness Speak to your doctor if this becomes troublesome.
Fluctuation in the desire to have sex Speak to your doctor if this becomes troublesome.
Dizziness Make sure your reactions are normal before driving, operating machinery, or doing other jobs which could be dangerous if you were not fully alert.
Breathing difficulties Speak to your doctor if this becomes troublesome.

How to store oxprenolol and cyclopenthiazide

  • Keep all medicines out of the reach of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Keep all medicines out of the sight and reach of children.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before taking this medicine tell your doctor if you have ever had an allergic reaction after taking any medicine.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if it is empty.
  • If you are having any treatment like an operation or dental treatment tell the person carrying out the treatment which medicines you are taking.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.
© EMIS 2007 DocID:
1466		 DocRef:
dils2638		 Last Updated:
22 Mar 2007		 Date of Next Review:
21 Mar 2009		 Version:
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PS - Health and Poverty

Perhaps the biggest cause of ill health in the world is poverty. Help to Make Poverty History. For example, why not lend some of your money to disadvantaged communities to enable them to trade their way out of poverty through schemes such as Shared Interest.

See also MAKEPOVERTYHISTORY North East for details and links to campaigns against poverty.

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