Lorazepam

  • Lorazepam is prescribed in short courses for anxiety or sleeplessness.
  • It can cause drowsiness and dizziness which may last into the next day.
  • Do not drink alcohol while you are being treated with lorazepam.

About lorazepam

Type of medicineBenzodiazepine
Used forAnxiety
Insomnia
Pre-medication before surgery
Status epilepticus (convulsions/fits)
Also calledAtivan®
Available asTablets and injection

Lorazepam is used for short periods of time to treat insomnia (difficulty sleeping) and for anxiety which is very troublesome. It is also used to reduce anxiety before surgery and to treat convulsions which last some time.

It works by affecting the part of the brain that controls emotion and also by relaxing muscles. This helps to reduce anxiety and promote sleepiness.

Before taking lorazepam

Before taking lorazepam make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have any breathing problems.
  • If you have liver or kidney problems.
  • If you have ever had a problem with drug or alcohol addiction.
  • If you have sleep apnoea syndrome (short periods in your sleep where you stop breathing).
  • If you have depression, a personality disorder, psychosis or any other mental health problem.
  • If you suffer from myasthenia gravis (a muscle-weakening disease) or any other muscle weakness.
  • If you suffer from porphyria (a blood disorder).
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or to any other medicine.

How to take lorazepam

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take lorazepam exactly as directed by your doctor.
  • Try to take lorazepam at the same time(s) each day to avoid missing any doses.
  • If you are taking lorazepam for sleeplessness and you forget to take a dose, do not worry. Just take the next dose when it is due.
  • If you are not taking lorazepam for sleeplessness and you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

Getting the most from your treatment

  • Keep your regular appointments with your doctor so that your progress can be checked.
  • Do not drink alcohol while you are taking lorazepam. It will increase the drowsiness you feel.
  • Lorazepam is usually prescribed for short periods of time only, from a few days up to four weeks. It should not normally be taken for longer periods of time, as this may lead to your feeling dependent on it. If you have already been taking lorazepam for longer periods of time than this, check with your doctor before stopping taking it. It must be stopped gradually as stopping suddenly can cause unpleasant withdrawal symptoms such as anxiety, tremor and sleeplessness.
  • If you buy any medicines while you are taking lorazepam, check with a pharmacist that they are safe to take together.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment that you are taking lorazepam.

Can lorazepam cause problems?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
Drowsiness, dizziness, feeling light-headed or less alert than normal. These effects may last into the next dayMake sure you know how you react to lorazepam before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Do not drink alcohol
Unsteadiness or muscle weakness, confusion, forgetfulnessLet your doctor know if these are troublesome

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store lorazepam

  • Keep all medicines out of the sight and reach of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF)
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2010DocID: 991DocRef: dils2635Last Reviewed: 14 Sep 2010Version: 23
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