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Gold salts

(Auranofin and sodium aurothiomalate)

  • Take auranofin with or after a meal.
  • Do not sunbathe or use sunbeds while you are being treated.
  • If you develop any side-effects from this treatment, discuss them with your doctor.

About gold salts

Type of medicine Disease-modifying antirheumatic drug (DMARD)
Used for Rheumatoid arthritis
Also called Ridaura® (as auranofin)
Myocrisin® (as sodium aurothiomalate)
Available as Tablets and injection

Gold salts can be used to relieve pain and inflammation in rheumatoid arthritis. There are two gold salt preparations that can be used - auranofin which is taken as a tablet and sodium aurothiomalate which is injected into a muscle.

Rheumatoid arthritis is a condition caused by the body's own immune system attacking itself. Gold salts work by suppressing the over-reaction of the immune system, although the exact way in which they do this is not fully understood.

Gold salts help relieve the symptoms and slow down the progress of rheumatoid arthritis; they will not cure the disease.

Before taking gold salts

Before taking gold salts make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from liver, kidney or breathing problems.
  • If you have ever suffered from a blood disorder, porphyria (a rare type of blood disorder), or bone marrow depression.
  • If you suffer from systemic lupus erythematosus (SLE).
  • If you suffer from eczema, flaky dermatitis, urticaria (a raised red itchy rash) or other similar skin condition.
  • If you suffer from inflammatory bowel disease (IBD), colitis or a similar bowel problem.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take gold salts

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take your medication exactly as directed by your doctor.
  • Take auranofin tablets with or immediately after food.
  • Try to take auranofin at the same times each day to avoid missing any doses.
  • If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.

Getting the most from your treatment

  • Keep your regular appointments with your doctor so your progress can be monitored. You will have regular blood tests while taking this medicine.
  • Do not stop taking this medicine without speaking to your doctor first. Gold salts may need to be taken for four to six months before you feel the full benefit.
  • Gold salts may cause skin exposed to sunlight to become discoloured. Avoid sitting in the sun and do not use sunbeds while you are taking this medicine.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you buy any medicines, check with a pharmacist that they are safe to take with gold salts.

Can gold salts cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects What can I do if I experience this
Diarrhoea (stomach pain and feelings of sickness can be associated with this) A high fibre diet may help. If the diarrhoea continues or contains blood, speak with your doctor straight away
Conjunctivitis, hair loss, skin rash and itchiness If any of these develop, tell your doctor

Important: If you develop a metallic taste in your mouth, a sore throat, fever, any unexplained bruising or bleeding, mouth ulcers, or a rash, speak with your doctor immediately or go to your local accident and emergency department without delay.

Important: If you develop a cough or breathlessness, let your doctor know as soon as possible.

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store gold salts

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • Manufacturer's PIL, Ridaura®, Astellas Pharma Ltd. electronic Medicines Compendium. August 2007, accessed 22 June 2008.
  • British National Formulary; 55th Edition (March 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008 DocID:
3419
DocRef:
dils2502
Last Updated:
13 Nov 2008
Date of Next Review:
13 Nov 2010
Version:
22
Patient UK Current Health News
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