Morphine

  • Morphine is used to treat severe pain or severe coughing.
  • Nausea, vomiting or constipation may occur with this medicine. Your doctor may be able to prescribe medicines to take with morphine to help with these side-effects.
  • Morphine can also cause drowsiness.

About morphine

Type of medicineStrong opioid analgesic
Used forPain relief or severe cough
Also calledMorphine sulphate
Depodur®
Oramorph®
Sevredol®
Filnarine® SR
Morphgesic® SR
MST Continus®
MXL®
Zomorph®
Available asTablet
Modified-release tablet
Modified-release capsule
Oral liquid
Sachets of modified-release oral liquid
Injection
Suppository

Morphine is used to relieve severe pain and severe coughs; it works on the nerves and brain to reduce the pain you feel or the need to cough.

Before taking morphine

Before taking morphine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have liver, kidney or prostate problems.
  • If you have heart rhythm problems.
  • If you have breathing problems, such as asthma.
  • If you have low blood pressure.
  • If you have thyroid problems.
  • If you suffer from convulsions.
  • If you have a problem in your bile duct.
  • If you have been constipated for more than a week or have an inflammatory bowel problem.
  • If you have phaeochromocytoma or other adrenal gland problem.
  • If you have myasthenia gravis (a muscle weakening disorder).
  • If you have recently suffered a serious head injury.
  • If you have ever had a problem with drug addiction.
  • If you have ever had an allergic reaction to this or to any other medicine.
  • If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines.

How to take morphine

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take morphine exactly as you have been directed by your doctor. Never take more than the prescribed dose.
  • If you have been given capsules, they can be swallowed whole, or opened and the contents sprinkled onto soft food such as yogurt.
  • Depending on the reason that you are taking morphine, your doctor may advise that you take it regularly or only when you need it for pain relief. Make sure you know which is right for you.

Getting the most from your treatment

  • Do not drink alcohol with morphine as this will increase the side-effects of dizziness and drowsiness.
  • Taking morphine regularly for a long time can lead to your body becoming dependent on it, which might cause you to feel restless and irritable when you stop taking it. If you are concerned about this, discuss the problem with your doctor or pharmacist.
  • If you are planning a trip abroad you are advised to carry a letter with you from your doctor because morphine is a controlled drug. If you plan to travel for more than 3 months, you must check with the Home Office before you travel as you will need to apply in writing for a licence to take morphine with you.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment that you are taking morphine.
  • If you buy any medicines, check with a pharmacist that they are safe to take with morphine.

Can morphine cause problems ?

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effectsWhat can I do if I experience this
Feeling or being sickThis usually passes after a few days, but let your doctor know if it continues. Your doctor may prescribe a medicine to ease the sickness
Drowsiness, difficulties with visionMake sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert or able to see clearly
ConstipationTry to eat a well balanced diet containing fibre and drink 6-8 glasses of water each day. If this continues your doctor may prescribe a laxative for you
Dry mouthTry chewing sugar-free gum or sucking sugar-free sweets
Dizziness, particularly when getting up from a sitting or lying positionGetting up slowly should help
Other side-effects include: palpitations, swollen legs or ankles, mood changes, confusion, sleep disturbances, headache, sexual difficulties, difficulty passing urine, sweating, rash, and itchingIf any of these become troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store morphine

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF)
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2010DocID: 1085DocRef: dils2474Last Reviewed: 4 Oct 2010Version: 23
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