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Lisinopril
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About lisinopril
| Type of medicine | ACE (angiotensin converting enzyme) inhibitor |
| Used for | High blood pressure (hypertension) Heart failure To help prevent problems after a heart attack Circulation problems associated with diabetes |
| Also called | Zestril® Carace Plus® (lisinopril with hydrochlorothiazide) Zestoretic® (lisinopril with hydrochlorothiazide) |
| Available as | Tablets |
Lisinopril works by causing blood vessels to relax, lowering blood pressure and increasing the supply of blood and oxygen to the heart. It can be used on its own or alongside other medicines which reduce blood pressure.
Before taking lisinopril
Before taking lisinopril make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from kidney or liver problems.
- If you have heart failure (a condition where the pumping action of the heart is reduced).
- If you suffer from a collagen vascular disease, such as systemic lupus erythematosus (SLE) or scleroderma.
- If you are on a salt restricted diet or use salt substitutes which contain potassium.
- If you have cardiomyopathy (cardiac muscle disease) or aortic stenosis (narrowing of the blood vessel from the heart).
- If you have atherosclerosis (the build up of fatty deposits on the walls of arteries).
- If you suffer from peripheral vascular disease (a particular type of poor circulation).
- If you have a history of angioedema (where the face, tongue and throat swell) or have ever had an allergic reaction to this or any other medicine.
- If you are having LDL apheresis (the removal of cholesterol from the blood by a machine).
- If you are having desensitisation treatment for bee and wasp stings.
- If you are having dialysis treatment.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take lisinopril
- Before beginning treatment you should read the manufacturer's printed information leaflet.
- Take lisinopril exactly as directed by your doctor.
- Try to take your dose at the same time each day to avoid missing any doses. It is usually taken during the day but your doctor may advise you to take your very first dose just before going to bed.
- If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up.
Getting the most from your treatment
- Keep your regular appointments with your doctor. You will probably need to have blood tests and blood pressure tests to ensure the dose you are taking is right for you.
- Try to avoid drinking too much alcohol as this will affect your blood pressure. If you do drink alcohol, drink only in moderation and be aware of its effects on you.
- Treatment with lisinopril is usually life-long. Do not stop taking this medicine without speaking to your doctor first.
- If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
- If you buy any medicines, check with a pharmacist that they are safe to take with lisinopril.
Can lisinopril cause problems?
Along with their useful effects all medicines can cause unwanted side effects. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Light-headedness or dizziness when getting up from a sitting or lying position especially the first time you take lisinopril | Getting up slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing. If this continues, speak with your doctor |
| Diarrhoea, abdominal pain, nausea, constipation | After a few days these will usually improve. If they continue, speak to your pharmacist or doctor |
| Dry cough | If you develop a prolonged dry cough, contact your doctor. An alternative medicine may be available that does not cause this problem |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If the headache continues, speak with your doctor |
| 'Pins and needles', muscle and joint pain, skin rash, itching, changes in taste, sinusitis, a blocked or runny nose, sore throat, difficulty breathing and an increased sensitivity to sunlight | Speak with your doctor if any of these are troublesome |
- If you experience swelling of the throat, tongue or face, go to the accident and emergency department of your local hospital immediately.
- If you experience chest pain, severe back pain, develop a severe sore throat, mouth ulcers, fever or jaundice (yellowing of the skin and whites of the eyes), speak with your doctor or go to your local accident and emergency department without delay.
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store lisinopril
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Zestril® 2.5mg, 5mg,10mg, and 20mg tablets, AstraZeneca UK Limited, electronic Medicines Compendium. Dated July 2008, accessed April 2009.
- British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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