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Mefloquine
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About mefloquine
| Type of medicine | Antimalarial |
| Used for | Treatment of malaria Prevention for travellers to countries with high levels of malaria |
| Also called | Lariam |
| Available as | Tablets |
Malaria is caused by parasites which can enter your body when you are bitten by a mosquito. Mefloquine works by attacking parasites once they have entered the red blood cells. It kills the parasites and prevents them from multiplying further.
Before taking mefloquine
Before taking mefloquine make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from liver problems.
- If you have a history of mental illness, or fits.
- If you suffer from heart problems.
- If you have had an allergic reaction to mefloquine or related compounds, e.g. quinine.
How to take mefloquine
Prevention:
- Started at least one week (and up to 2 - 3 weeks) before travel.
- Doses are taken once a week, and for four weeks after return.
- Tablets should be swallowed whole, after a meal, with a glass of water
Treatment:
- Dose should be taken as directed by your doctor.
Getting the most from your treatment
Prevention:
- Start mefloquine two and a half weeks before departure, as this allows you to get used to the medicine, or see your doctor if you get side effects.
- If you feel dizzy you should not drive or operate machinery.
- Avoid being bitten by using screened doors and windows, room insecticides, wearing light-coloured clothing that covers the arms and legs, using insect repellents such as DEET or lemon eucalyptus-based products.
- See your doctor if you are ill within 1 year of your holiday, and tell your doctor that you have been to a malarious area.
Can mefloquine cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Side-effects | What can I do if I experience this |
| Nausea, vomiting | Eat little and often. Stick to simple foods such as dry toast. If you are sick, drink plenty of liquid. |
| Loose stools or diarrhoea | Drink plenty of water to replace lost fluids. |
| Dizziness, loss of balance | Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. |
| Changes in mood, low mood | See your doctor as soon as possible. |
How to store mefloquine
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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| © EMIS 2007 | DocID: 3351 |
DocRef: dils2341 |
Last Updated: 8 Feb 2007 |
Date of Next Review: 7 Feb 2009 |
Version: 22 |
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