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Diazepam rectal

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  • Rectal diazepam preparations are used to treat convulsions caused by epilepsy or fever.
  • They are useful if a quick effect is needed or when it is not possible to administer the medicine by mouth.
  • After using this medicine many people can feel sleepy, dizzy, clumsy or light-headed.
  • Do not drink alcohol with diazepam as it will increase the feelings of drowsiness.

About rectal diazepam

Type of medicineBenzodiazepine
Used forConvulsions (fits)
Also calledStesolid®
Diazepam Rectubes®
Valclair®
Available asRectal tubes
Suppositories

Diazepam can be used to stop convulsions (fits) and to relax muscles.

Rectal diazepam preparations are used to treat convulsions caused by epilepsy or fever. They are administered into the back passage and are useful if a quick effect is needed or when it is not possible to administer the medicine by mouth.

Before using rectal diazepam

Before using rectal diazepam make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from any respiratory (breathing) problems.
  • If you suffer from liver or kidney problems.
  • If you suffer from myasthenia gravis (a muscle weakening disease).
  • If you suffer from porphyria (a blood disorder).
  • If you suffer from a personality disorder.
  • If you have ever had a problem with drug or alcohol addiction.
  • If you suffer from sleep apnoea (temporary stopping of breathing during sleep).
  • If you suffer from phobias or obsessional conditions.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to give rectal diazepam

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Try to lie the patient on their side with their knees drawn up towards their chest and with one leg drawn up more than the other.

Using rectal tubes:

  1. Remove the cap from the rectal tube.
  2. Insert the tube into the rectum (back passage) as far as the mark on the nozzle. NOTE: If this medicine is for a child under 3 years of age, the tube should be inserted only half way between the mark and the tip of the nozzle.
  3. Empty the contents completely by squeezing the tube between the index finger and thumb.
  4. When the tube is empty, keeping it squeezed, remove it from the back passage and then throw it away.
  5. After giving the dose, hold the patients buttocks together for a few minutes to prevent any seepage and then lower the patient's legs to a comfortable position. The patient may feel an immediate urge to go to the toilet. Encourage them to ignore this.
  6. Your doctor will have told you what to do if no effect is seen after 5-10 minutes. If you are unsure, contact your doctor for assistance.

Using suppositories:

  1. Remove the wrapping from the suppository.
  2. Gently insert the suppository into the rectum (back passage), pointed end first, as far as it will go.
  3. If the suppository comes out immediately, it was not inserted far enough, and it should be reinserted.
  4. After giving the dose, lower the patient's legs to a comfortable position to help hold the medicine in place. The patient may feel an immediate urge to go to the toilet. Encourage them to ignore this.

Getting the most from this treatment

  • Suppositories are usually easier to insert if they have been stored in the fridge.
  • Keep regular appointments with the your doctor so that your progress can be checked.
  • After using rectal tubes many people feel drowsy, dizzy, light-headed, clumsy, unsteady or less alert than normal - feelings which can can last for several hours. The patient should be allowed to sleep after receiving this treatment and must not do any jobs that require them to be fully alert, like driving or operating machinery, until any drowsiness has disappeared. Drinking alcohol will increase these feelings of drowsiness so do not drink alcohol while you are taking diazepam.
  • If given continuously for too long, there is a risk of becoming dependent on diazepam which will cause problems when the treatment is stopped. If you are concerned about this, discuss it with your doctor.
  • If you buy any medicines, check with a pharmacist that they are safe to take with diazepam.

Can rectal diazepam cause problems?

Along with their useful effects all medicines can cause unwanted side-effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
Drowsiness, dizziness, feeling light-headed and unsteadinessThis feeling can carry on the following day. The patient should avoid doing anything that requires them to be fully alert until any drowsiness has disappeared
Shallow breathing, feeling (or being) aggressiveLet your doctor know about this

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store rectal diazepam

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • Manufacturer's PIL, Diazepam Rectal Tubes, Wockhardt UK Ltd, electronic Medicines Compendium. Revised February 2004, accessed May 2009.
  • British National Formulary; 57th Edition (March 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2009 DocID: 3337 DocRef: dils2311 Last Reviewed: 5 Nov 2009 Version: 22

The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.

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