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Loperamide
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About loperamide
| Type of medicine | Antimotility drug |
| Used for | Diarrhoea |
| Also called | Diocalm®, Entrocalm®, Imodium®, Imodium® Instants, Norimode®, Normaloe® |
| Available as | Capsules Tablets Chewable tablets Orodispersible tablets (dissolve-in-the-mouth) Oral liquid |
Loperamide works by slowing down the movement of the intestine and reducing the speed at which the contents of the gut pass through. Food remains in the intestines for longer and water can be more effectively absorbed back into the body. This results in firmer stools that are passed less often.
Before taking loperamide
Before taking loperamide make sure your doctor or pharmacist knows:
- If you suffer from liver problems.
- If you suffer from colitis (inflammation of the bowel).
- If you have a condition where slowing of the bowel should be avoided, for example, constipation or bloated tummy.
- If you are pregnant, trying for a baby or breast-feeding.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
Loperamide is not recommended in children under 4 years.
How to take loperamide
- Take loperamide exactly as directed. The usual dose for an adult is two tablets or capsules to start with, followed by one tablet or capsule after each loose bowel movement. This usually means taking three or four doses a day. Never take more than 8 tablets or capsules each day. If the loperamide is for a child, the dose will depend upon the child's age. If you are unsure of what dose to give, speak to your doctor.
- Swallow loperamide capsules and tablets whole, not crushed or chewed, with a glass of water.
- Suck or chew loperamide chewable tablets before swallowing.
- Allow loperamide orodispersible tablets to dissolve in the mouth.
Getting the most from your treatment
- In addition to taking loperamide, oral rehydration salts may be taken to help prevent dehydration and replace lost salts. Check with your pharmacist before taking that these are suitable for you.
- Make sure you also drink plenty of clear fluids such as water or very diluted squashes or fruit juices. Avoid drinking alcohol or milk.
- As your diarrhoea begins to improve try eating more solid foods.
- If your symptoms persist for more than 24 hours consult your doctor or pharmacist for advice, if you have not already done so. If loperamide has been prescribed by your doctor, and symptoms have not settled after 5 days, return for further advice.
- If symptoms get worse or you have a fever (high temperature) ask your doctor or pharmacist for advice.
Can loperamide cause problems
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Possible side-effects | What can I do if I experience this |
| Abdominal cramps and bloating | Speak to your doctor or pharmacist if these symptoms continue |
| Dizziness, drowsiness | Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert |
| Skin reactions including rashes and itching | Speak to your doctor or pharmacist if these symptoms occur |
Other side-effects include nausea (feeling sick), vomiting, indigestion and difficulty passing urine. If you experience these or any other worrying symptoms, which you think may be due to this medicine, discuss them with your doctor or pharmacist.
How to store loperamide
- Keep all medicines out of the sight and reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- British National Formulary; 56th Edition (September 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
- Manufacturer's PIL, Imodium® Capsules and Syrup, Janssen-Cilag Ltd, electronic Medicines Compendium. Revised August 2003, accessed September 2008.
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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