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Doxepin cream

  • Doxepin belongs to the group of medicines known as antipruritics. They can help to stop itching of the skin.
  • Covering the skin with dressings after applying topical doxepin can increase the absorption of the medicine and therefore increase the risk of side effects. Do not apply dressings unless you have been told to do so by your doctor.
  • Drowsiness or burning, stinging or tingling sensation of the skin are the most common side effects.

About doxepin cream

Type of medicineAntipruritic
Used forItching often due to eczema
Also calledXepin®
Available asCream

Scratching areas of eczema can cause the body to produce a chemical called histamine. The release of histamine causes further itching. Antipruritics stop the effects of histamine and help to relieve itching.

Before using doxepin cream

Before using doxepin cream make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If the cream is for a child under 12 years of age.
  • If you suffer from liver problems.
  • If you suffer from mental health problems.
  • If you suffer from glaucoma (increased eye pressure).
  • If you have difficulty urinating (passing water).
  • If you have ever had an allergic reaction to this or any other medicine.
  • If you are taking or using any other medicines, including those available to buy without a prescription, herbal and complementary medicines.

How to use doxepin cream

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Apply doxepin cream thinly to the affected area as directed by your doctor. This is usually three or four times each day.

Getting the most from your treatment

  • Do not apply doxepin cream to broken skin.
  • Avoid contact with the eyes. If any of this preparation gets into the eyes rinse the area thoroughly with warm water.
  • Covering the skin with dressings after applying topical doxepin can increase the absorption of the medicine and therefore increase the risk of side effects. Do not apply dressings unless you have been told to do so by your doctor.
  • Extremes of temperature, wearing rough or irritating clothing such as wool can make your itching worse.

Can doxepin cream cause problems?

Along with their useful effects all medicines can cause unwanted side effects which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who use this medicineWhat can I do if I experience this
Burning, stinging or tingling sensation of the skinIt may improve as you get used to the cream. If it continues to be a problem and prevents you from using the cream speak with your doctor
DrowsinessMake sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert.
Avoid alcohol; it will increase any feelings of drowsiness
Headache, dry mouth, fever, dizzinessIf any of these become troublesome, speak to your doctor

How to store doxepin cream

  • Keep all medicines out of the reach of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Keep all medicines out of the sight and reach of children.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before taking this medicine tell your doctor if you have ever had an allergic reaction after taking any medicine.
  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Always take the container with you, if possible, even if it is empty.
  • If you are having any treatment like an operation or dental treatment tell the person carrying out the treatment which medicines you are taking.
  • Always read the printed information leaflet that comes with your medicine.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 56th Edition (September 2008) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2008DocID:
3221
DocRef:
dils2076
Last Reviewed:
17 Nov 2008
Version:
23
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