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Prochlorperazine
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About prochlorperazine
| Type of medicine | Neuroleptics |
| Used for | Mental illness (such as hearing, seeing or sensing things that are not real, mistaken beliefs and problems dealing with other people). It is also used in lower doses for nausea (feeling sick), vomiting (being sick), dizziness and problems with balance. |
| Also called | Buccastem® Stemetil® |
| Available as | Tablet, buccal tablet (dissolve in the mouth), oral liquid and injection form |
Prochlorperazine is used to treat mental illness with symptoms such as hearing, seeing or sensing things that are not real, mistaken beliefs and problems dealing with other people. It is also used to treat conditions not associated with mental illness such as nausea (feeling sick), vomiting (being sick), dizziness and problems with balance.
Before taking prochlorperazine
Before taking prochlorperazine make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from any heart problems
- If you suffer from liver, kidney or breathing problems
- If you suffer from Parkinson's disease, epilepsy, depression, myasthenia gravis (a muscle weakening disease), phaeochromocytoma (a growth on the adrenal glands), prostate problems, porphyria (a blood disorder) or glaucoma
- If you suffer from postural hypotension (if you become dizzy when getting up from a sitting or lying position)
- If you suffer from hypotension (low blood pressure)
How to take prochlorperazine
- If you have been supplied the standard 5 mg tablets, take these in the normal way by swallowing them with a glass of water.
- If you have been supplied the 3 mg buccal tablets (Buccastem®), the advised dose should be placed high between the upper lip and gum and left to dissolve. Do not use the standard 5mg tablets in this way.
- If you are prescribed a regular dose, try to get into the habit of taking this medicine at the same times each day to avoid missing any doses. Prochlorperazine can also be taken as required when treating sickness.
- Do not stop taking these tablets without first speaking with your doctor. Your doctor will probably want to reduce the dose you are taking gradually, as stopping treatment suddenly can cause complications.
Getting the most from your treatment
- You may have to take this medicine for several weeks before you feel the full effect.
Can prochlorperazine cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Dizziness | Make sure your reactions are normal before driving, operating machinery or doing any other jobs which could be dangerous if you were not fully alert. Avoid alcohol; it will increase any feelings of drowsiness |
| Headache | Ask your pharmacist to recommend a suitable pain-killer. If headache continues speak with your doctor. |
| Dry mouth | Try chewing sugar-free gum, sucking pieces of ice or sugar-free sweets. If this becomes troublesome speak to your pharmacist or doctor. |
| Constipation | Try to eat a well balanced diet containing plenty of fibre and drink 6-8 glasses of water each day. If constipation continues to be a problem speak to your pharmacist or doctor. |
| Blurred vision | Make sure that you can see properly before starting any task that may be dangerous if you could not see very well. |
| Diarrhoea | Drink plenty of water to replace lost fluids. If diarrhoea continues to be a problem speak to your pharmacist or doctor. |
| Shakiness, abnormal face and body movements, restlessness, uncontrollable movements of the tongue face and jaw, drowsiness, mood changes, insomnia (trouble sleeping), confusion, problems urinating (passing water), a fast or thumping heartbeat, changes in menstruation (periods), breast problems, sexual problems, weight gain, skin rashes, jaundice (yellowing of the skin and whites of the eyes), purple tint to the skin and eyes. | Speak with your doctor if you suffer from any of these problems. |
How to store prochlorperazine
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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