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Immune Thrombocytopenia, Synonym: immune thrombocytopenic purpura Immune thrombocytopenia (ITP) describes an autoimmune disorder in which the number of circulating platelets i...
Thrombocytopenia and Platelet Function Disorders, Thrombocytopenia means a reduction in the platelet count below the normal lower limit, which is usually defined as 150 x 10 9 /L [...
The platelets are large and have a grey appearance on light microscopy. [ 1 ] It is one of the macrothrombocytopenias, which are inherited thrombocytopenias with increased platelet size. [ 2...
Synonyms: t hrombocytopenia with a bsent r adius (hence TAR) syndrome, tetraphocomelia-thrombocytopenia syndrome Epidemiology This is a rare autosomal recessive condition. Th...
Synonyms: giant platelet syndrome This is a congenital bleeding disorder characterised by thrombocytopenia and large platelets. Pathogenesis The molecular defect involves the absence o...
Low blood platelets (thrombocytopenia) Thrombocytopenia means you have a low blood platelet count. Platelets (thrombocytes) are cells in the blood that help the blood to clot by c...
Autoantibodies may be detected if autoimmune disease is present, especially in autoimmune haemolytic anaemia and immune thrombocytopenia and neutropenia. Consider the diagnosis in boys wit...
Investigations [ 1 ] Full blood count may show leucopenia and thrombocytopenia . Laboratory testing for the virus will depend on local availability, but the following techniques ...
Erythroleukaemia: characterised by a prominence of myeloblasts in the bone marrow, amegakaryocytic thrombocytopenia and reduced granulopoiesis, leading to neutropenia. Acute myeloid leuka...
It is characterised by: Haemolysis (H) Elevated Liver enzymes (EL) Low Platelet count (LP) NB : most isolated cases of thrombocytopenia in pregnancy are due to gestational ...
For example, they may be done to: Find the reason for a low number of red blood cells (anaemia), a low number of white blood cells (leukopenia), or a low number of platelets (thrombocytopeni...
Other causes of thrombocytopenia - eg, immune thrombocytopenia or drugs. Chronic myeloid leukaemia . Bone marrow failure .
It is characterised by: Microangiopathic haemolysis. Thrombocytopenia. Neurological abnormalities. Fever. Renal dysfunction. The diagnosis of TTP should be treated as ...
Too few platelets , which is called thrombocytopenia. This may make you bruise or bleed easily. There are various causes. Too many platelets , which is called thrombocythaemia (or thrombo...
Presentation [ 6 , 7 ] Type 1 Gaucher's disease May present with chronic fatigue, hepatomegaly, splenomegaly (may become massive), and bone involvement (bone pain due to bone infarcts o...
Haematological : atypical mononucleosis (lymphocytosis); thrombocytopenia or bone marrow failure . CNS : meningitis or encephalitis, hepatic encephalopathy .
Excessive platelet destruction such as: Immune problems (eg, immune thrombocytopenia , secondary immune thrombocytopenia - SLE, viral infections, drugs - post-transfusion purpu...
Thrombocytopenic , or thrombocytopenia, means not having enough platelets. Purpura is a purple-red rash. It is caused by tiny bleeds under the skin. , Immune thrombocytopenia...
Too few platelets - this is called thrombocytopenia . This may make you bruise or bleed easily. There are various causes. Too many platelets - this is called thrombocythaemia ( or thro...
Bleeding disorders There are various conditions where you tend to bleed excessively if you damage or cut a blood vessel - for example: Too few platelets (thrombocytopenia) - due to...