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Hereditary Spherocytosis, What is hereditary spherocytosis? Hereditary spherocytosis (HS) is an inherited condition that affects your red blood cells. , Hereditary sp...
Hereditary Spherocytosis, Neonates with severe hereditary disease do not always present at birth with anaemia, but haemoglobin may fall dramatically over the first few weeks of life and may b...
Haemolytic anaemia causes (aetiology) Genetic Red cell membrane abnormalities: hereditary spherocytosis , elliptocytosis. Haemoglobin abnormalities: sickle cell anaemia , thala...
The only times the illness may become more serious are: In children with some types of hereditary anaemia such as sickle cell disease , beta-thalassaemia and hereditary spherocytosis...
See the separate leaflet called Hereditary Spherocytosis as an example of a condition with abnormal red blood cells . It also stores up to one third of the body's supply of platelets.
Haemolysis: hereditary spherocytosis, sickle cell anaemia, thalassaemia. Neoplasia: acute lymphoblastic leukaemia (ALL), Hodgkin's disease and non-Hodgkin's lymphoma (NHL), acute o...
Conditions that cause an increased rate of breakdown of red blood cells include: Some genetic diseases, such as sickle cell anaemia , thalassaemia , spherocytosis, and glucose 6-phosp...
Also, the spleen may not work well in some diseases - for example, sickle cell disease , thalassaemia , hereditary spherocytosis and lymphomas . Want to see a dietician? ...
Gilbert's syndrome may present in the newborn, especially if there is concurrent haemolysis such as ABO incompatibility; it has also been associated with breast milk jaundice. [ 3 ] Associa...
Genetic conditions where there is an abnormality in the red cell membrane such as hereditary spherocytosis , or elliptocytosis. Conditions where there are haemoglobin abnormalities such as ...
Anaemia due to increased red blood cell destruction (haemolysis) Genetic : Red cell membrane defects - including hereditary spherocytosis. Red cell enzyme abnormalities - inclu...
Symptoms of kernicterus (presentation) [ 7 ] There may be known risk factors such as prematurity, rhesus incompatibility or a family history of G6PD deficiency or spherocytosis. ABO inco...
Exacerbation of other haemolytic anaemias - eg, hereditary spherocytosis , autoimmune haemolytic anaemia . Disseminated intravascular coagulation . Systemic lupus erythematosus...
Hereditary spherocytosis . Hereditary elliptocytosis. Lymphomas and leukaemias. See the separate leaflets called Spleen Pain and Preventing infection after Splenectomy for mo...
Chronic haemolysis ( hereditary spherocytosis ). Paroxysmal nocturnal haemoglobinuria . Leukaemia. Gastrointestinal bleeding.
Low ESR: polycythaemia, hypofibrinogenaemia, congestive cardiac failure, spherocytosis, sickle cells. The ESR is more useful than serum CRP for diagnosis and monitoring of polymyalgia rheu...
Disorders of red cell production - eg, congenital dyserythropoietic anaemia, Diamond-Blackfan syndrome, lethal hereditary spherocytosis, congenital erythropoietic porphyria (Günther'...
Hereditary spherocytosis and familial pseudohyperkalaemia (potassium leaks from cells as a result of cooling).
Hypersplenism: hereditary spherocytosis or elliptocytosis, immune thrombocytopenia . Neoplasia: lymphoma or leukaemic infiltration.
More rarely, a systemic loxoscelism can give rise to fever, morbilliform rash, jaundice, intravascular haemolysis associated with spherocytosis, haemoglobinuria/acute kidney injury, seizures ...