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Sickle Cell Disease (Sickle Cell Anaemia), Note : a fever can occur in a sickle cell crisis without having an infection. Sickle cell a...
Sickle Cell Disease and Sickle Cell Anaemia, Sickling disorders include heterozygous (AS) sickle cell trait, homozygous (SS) sickle c...
Sickle Cell Trait, If you inherit a gene from one of your parents, called a sickle cell gene, you have a condition called sickle cell trait. If yo...
They should not travel for 10 days following a crisis [ 1 ] . Patients with sickle cell trait can usually travel without restriction. Ear, nose and throat problems ...
Genetic defect causes production of abnormal Hb with a red blood cell life of ≤15 days. In a sickle cell crisis, red blood cell destruction causes severe haemolytic anaemia ...
Stem Cell Transplant, In the management of sickle cell disease . Where are stem cells obtained from? An autologous transplant This means that the ste...
Lower lobe pneumonia . Sickle cell crisis . Hypercalcaemia . Hereditary angio-oedema . Gynaecological/obstetric Ectopic pregnancy - may present with nonspecific symptoms - eg, sy...
Splenic infarction - eg, with sickle cell crisis . Acute splenic sequestration - eg, a child with sickle cell disease and acute anaemia.
Others: sickle cell crisis , diabetic mononeuritis, tabes dorsalis. Assessment The aim is to exclude a life-threatening cause, which needs immediate treatment, from other causes o...
Hyperthyroid Crisis (Thyrotoxic Storm), Synonyms: thyrotoxic crisis, thyroid storm, hyperthyroid storm Hyperthyroid crisis, or thyrotoxic storm, is an extreme manifes...
Medical problems - lower lobe pneumonia, pulmonary embolus, diabetic ketoacidosis, sickle cell crisis, myocardial infarction (may present with abdominal pain). Fetal distress. ...
Renal stones . Sickle cell crisis . Urinary tract infection . Investigations [ 16 ] Laboratory investigations The diagnosis is usually made clinically and management sho...
Non-surgical disease - eg, myocardial infarction , pericarditis, pneumonia , sickle cell crisis , hepatitis , inflammatory bowel disease, opiate withdrawal, typhoid , acute intermittent...
Adrenal Crisis, Synonym: Addisonian crisis Adrenal crisis is a potentially fatal condition associated mainly with an acute deficiency of the glucocorticoid cortisol a...
Crisis Intervention, What is a crisis? A crisis occurs when an individual feels overwhelmed by events. The crisis may be precipitated by events which bring abo...
Mastocytosis and Mast Cell Disorders, What are mast cells? Mast cells are a type of white blood cell - together, our white blood cells play a major role...
Temporal Arteritis (Giant Cell Arteritis), It is called 'giant cell' because abnormal large cells develop in the wall of the inflamed arteries. The arteries commonly...
Langerhans' Cell Histiocytosis, What is Langerhans' cell histiocytosis? (Definition) [ 1 ] Langerhans' cell histiocytosis (LCH) is one of the 'histi...
Mastocytosis and Mast Cell Disorders, Synonym: systemic mast cell disease What is mastocytosis? Mast cells are found in the perivascular spaces of most tissues and...
Polycythaemia Rubra Vera (High Red Blood Cell Count), Stem cells constantly divide and produce new cells. Some new cells remain as stem cells and others go...