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Other risk factors which have been suggested include viral infections, younger age, prior treatment with prednisone, B negative blood type, and use of halothane anaesthesia. [ 1 ] Symp...
Editor's note Dr Krishna Vakharia , 15th February 2024 For those adults who cannot have or do not want chemotherapy and who have untreated hormone-relapsed p...
Management includes aggressive and prolonged administration of antibiotics and prednisone. Treatment of manifestations A definitive microbiological diagnosis is essential.
Various corticosteroid regimens including oral prednisone, high doses of intravenous pulse corticosteroids, and adrenocorticotrophic hormone (ACTH) have been reported to be effective. [ 2 ] ...
Systemic corticosteroid therapy (prednisone 0.5 mg/kg/day) is the treatment of choice for severe forms. For maintenance treatment, doses may be tapered gradually within 4-6 months of initiati...
Management [ 1 , 11 ] There is no effective treatment for the disease and few high-quality randomised controlled trials. [ 12 ] Treatment is challenging as the disease is typically resistant to s...
Steroids have no proven added benefit over plasmapheresis alone, but some patients respond to high-dose prednisone (200 mg/day) alone, without plasma therapy. Haemorrhage is a concern with...
Probably the best documented of these is haloperidol but valproate is now most specialists' first-line choice. [ 20 ] Dopamine receptor-blocking drugs such as pimozide are used for non-respon...
A Cochrane review found no significant benefit for treatment with steroids, antiplatelet agents or cyclophosphamide. [ 11 ] However, randomised trials have demonstrated success with high-dose ste...
Pre-phase therapy with corticosteroids (usually prednisone or dexamethasone) alone, or in combination with another drug (eg, vincristine, cyclophosphamide), is often given together with allop...
Cabazitaxel in combination with prednisone or prednisolone is recommended as an option for treating metastatic hormone-relapsed prostate cancer in people whose disease has progressed during o...
Corticosteroids (at least 60 mg prednisone or prednisolone) and amitriptyline (up to 50 mg) are possibly effective in the treatment of withdrawal symptoms.
Tocilizumab (a monoclonal antibody against the interleukin-6 receptor) is an effective glucocorticoid-sparing therapy, demonstrating sustained glucocorticoid-free remission in 56% of patients receivin...