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Myelodysplastic Syndromes, Fibrotic MDS - although almost half the patients have an element of bone marrow fibrosis, this is marked in about 15% of patients (more commonly in secondary MDS); ...
Other haematological diseases which cause thrombocytosis are myeloproliferative, myelodysplastic or a combination of both.
Malignancy-associated: More commonly reported with haematologic malignancies and myeloproliferative or myelodysplastic disorders compared to solid-organ malignancies. The most ...
Associated diseases Idiopathic MF is a chronic myeloproliferative disorder, along with chronic myeloid leukaemia, polycythaemia rubra vera and essential thrombocytosis. , My...
Elliptocytes oval (ovalocyte) or cigar-shaped cells (cigar cell) that occur in hereditary elliptocytosis, myeloproliferative disorder and myelodysplastic syndrome. Subtype: pencil/r...
Malignancy - eg, leukaemias, lymphomas, myeloproliferative neoplasms, solid cancers (especially gastrointestinal, breast or lung). Myelodysplastic syndromes. Investigations A...
Identified risk factors include myelodysplastic disorders, some congenital disorders (eg, Down's syndrome , neurofibromatosis ), and benzene exposure.
Patients who have survived cancer chemotherapy are at risk. [ 10 ] Those who have had alkylating agents, with or without radiation, often have a myelodysplastic condition that can progress t...
Acquired vWD may occur in patients with aortic stenosis and has also been described in association with other conditions - eg, Wilms' tumour, hypothyroidism. Myeloproliferative disorde...
Myelodysplasia and myeloproliferative diseases. Investigations [ 5 ] Blood FBC shows a minimum clonal B cell lymphocytosis (>5 x 10 9 lymphocytes/L, may be ≥30...