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They include azathioprine , ciclosporin , penicillamine , hydroxychloroquine , leflunomide , methotrexate , mycophenolate mofetil (MMF) , sodium aurothiomalate and sulfasalazine . ,...
First-line treatment with cDMARD monotherapy using oral methotrexate, leflunomide or sulfasalazine should be started as soon as possible and ideally within three months of onset of persistent...
Types of disease-modifying antirheumatic drugs [ 1 , 4 ] Broadly, DMARDs are categorised as: Conventional DMARDs (cDMARDs) or non-biological DMARDs . cDMARDs (oral methotrexate , lef...
Cyclophosphamide . Leflunomide . These medicines are used to treat all sorts of conditions, some of the more common ones including: Cancers such as lymphoma or leukaemia.
Various disease-modifying antirheumatic drugs (DMARDs) have been used with mixed success and few data are available on the use of biological agents that might even increase the infection risk. [ 2 ] ...
DMARDs used for JIA include: Methotrexate Sulfasalazine Leflunomide Biological medicines are another group of medicines used by specialists to help symptoms and reduc...
Disease-modifying antirheumatic drugs ( DMARDs ) : In patients with active disease (particularly those with many swollen joints, structural damage in the presence of inflammation, high ESR or CR...
Once the patient is in remission, cyclophosphamide should be replaced by azathioprine or methotrexate. Leflunomide or mycophenolate may be given as alternatives if there is intolerance or lac...
Other treatments tried are rituximab and leflunomide have also been reported in small studies to be of benefit. In chronic HP with progressive fibrosis, antifibrotic agents have been...
DMARDs include methotrexate , sulfasalazine , leflunomide and hydroxychloroquine . It is these medicines that have improved the outlook in recent years for many people with RA. , Arth...
Prednisolone Methotrexate Azathioprine Wegener's granulomatosis Vasculitis Cyclophosphamide Mycophenolate mofetil Leflunomide Rituximab
If this is unsuccessful, some patients may respond to the addition of cyclophosphamide, ciclosporin, tacrolimus, mycophenolate mofetil (MMF), mizoribine, or leflunomide. A large proportion...
Sulfasalazine and leflunomide may be used for JIA. NICE guidance [ 11 ] The National Institute for Health and Care Excellence (NICE) recommends abatacept, adalimumab, etanercept ...
Standard disease-modifying antirheumatic drugs (DMARDs), such as methotrexate, leflunomide or sulfasalazine, can be used for patients with peripheral polyarthritis, oligoarthritis, or persist...
Drugs, including ciclosporin, cocaine and other substances of abuse, the combined oral contraceptive, corticosteroids, erythropoietin, leflunomide, (present in some herbal medicines), non-ste...
The antimetabolites (eg, methotrexate, azathioprine, leflunomide and mycophenolate) are considered second-line agents and used as alternatives to steroids. , Prednisolone Methotrexate Azat...
They can accompany amlodipine, antimalarials, beta-blockers, captopril, diflunisal (now withdrawn), diltiazem, enalapril, furosemide, glimepiride, gold, leflunomide, penicillamine, phenothiaz...
Second-tier agents include hydroxycarbamide, mycophenolate, sulfasalazine, azathioprine and leflunomide. Biological therapies - etanercept, efalizumab, adalimumab, infliximab and uste...