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Subsequent management depends on the risk of recurrence according to the prediction of tumour behaviour. Imatinib is a selective kinase inhibitor which binds to activated c-KIT receptors a...
TKIs Imatinib : Imatinib was one of the first drugs designed on an understanding of a disease's molecular biology.
You may be advised to have one or more of the following treatments: Imatinib tablets . This medicine is known as a tyrosine kinase inhibitor. The chemical tyrosine kinase is made by th...
For example, myeloproliferative hypereosinophilic syndrome with a FIP1L1-PDGFRA mutation can be treated with imatinib . Congestive failure is treated in the usual way with diuretics,...
Biologics such as imatinib, adalimumab and etanercept. Epidemiology [ 1 , 2 ] Pityriasis rosea is most common in children and young adults, aged 10-35 years.
Nilotinib and imatinib - used, for example, in the treatment of chronic myeloid leukaemia (CML) and gastrointestinal stromal tumours (GISTs) . [ 9 ] Bilirubin may have protective eff...
Anti-neoplastic agents such as imatinib, irinotecan and docetaxel may have reduced efficacy when used concurrently. [ 23 ] Patient interaction warnings are frequently inadequate...
These malignancies are treated with wide local excision. Imatinib has been shown to decrease plexiform neurofibroma size. In NF2, sensorimotor polyneuropathy may be seen and there may be i...
In some cases, more intensive treatments such as imatinib, or drug combinations, may be considered [ 27 ] . The National Institute for Health and Care Excellence (NICE) recommends midostau...
CML (see also the separate Chronic Myeloid Leukaemia article): CML is treated very successfully with imatinib anti-tyrosine kinase therapy in adults and this is being evaluated...