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Synonyms: malignant hyperpyrexia, malignant hyperthermia susceptibility, MHS, hyperthermia of anaesthesia, King syndrome, King-Denborough syndrome What is malignant hyperthermia? , Mal...
Often, there is sudden onset of severe hyperthyroidism with [ 4 ] : Hyperpyrexia (over 41°C), dehydration. Heart rate greater than 140 beats per minute (with or without atrial ...
The condition shares many features with the serotonin syndrome and malignant hyperpyrexia. It presents a diagnostic challenge. Epidemiology [ 2 ] Pooled data from 1966 to 1997 sug...
If suspicious, outline risks and offer immediate referral to secondary care - may need blood cultures, and antibiotics - eg, gentamicin. Hyperpyrexia - consider 'ecstasy' [ 6 ] ; ...
Physical agents Electric shock Hyperpyrexia Radiation/radiotherapy Investigations [ 1 , 7 ] ECG: changes may include ST-segment elevation/depression, T-wave inver...
Risk factors for death include: [ 1 ] Children and the elderly Late presentation Pulmonary oedema, CNS features, hyperpyrexia Metabolic acidosis Salicylate concentration ab...
Anaesthesia can be a problem, as some patients with some forms of arthrogryposis are at risk of malignant hyperpyrexia. [ 8 ] Social and psychological care This encompasses some fund...
There may be hyperpyrexia. Hypotension and tachycardia can develop secondary to dehydration and hypovolaemia.
Temperature regulation Hypothermia and hyperpyrexia can result from disruption of the various temperature regulatory mechanisms. Sweating, shivering and vasoactive reflexes can be affected.
If there is a history of recent inhalational anaesthetic, consider malignant hyperpyrexia . Recreational drug toxicity, particularly involving cocaine, amfetamines and ecstasy, is an incr...
Idiosyncratic reactions related to specific agents - eg, malignant hyperpyrexia with suxamethonium, succinylcholine-related apnoea. Iatrogenic - eg, pneumothorax related to central line ...
Malignant hyperpyrexia caused by anaesthetic gas or suxamethonium (rare). Prolonged apnoea after suxamethonium caused by pseudocholinesterase deficiency (rare).