Showing 1 - 20 of 508 results filtered by
In life-threatening bleeds, fresh frozen plasma (FFP) should be administered prior to vitamin K. Vitamin K is available as phytomenadione (vitamin K) and as the synthetic water-soluble ana...
Plasma exchange should be initiated as soon as possible, preferably within 4-8 hours. [ 1 ] Infusion of fresh frozen plasma (FFP) 30 mL/kg can be used until the patient can be transferre...
In the UK the National Institute for Health and Care Excellence (NICE) recommends that magnesium sulfate should be considered but that neither dexamethasone nor betamethasone should be used in the tre...
Blood products (antithrombin III, recombinant activated protein C, recombinant factor VIIa, dried factor VIII, IX and XIII fractions, protein C concentrate and fresh frozen plasma) can also b...
A platelet count of less than 50 with active bleeding requires platelet transfusion and fresh frozen plasma to try to make up for depleted clotting factors. Coagulopathy may be a marker al...
Large supplies of blood and blood products, including platelets and fresh-frozen plasma, should be readily available. Arrange theatre immediately. The aim of surgery in an unstable pati...
Fluid/volume replacement Packed red blood cells or fresh frozen plasma for anaemia and shock. Sodium bicarbonate infusion (carefully) for metabolic acidosis.
Patients who are able should administer their normal factor VIII, as advised by their haemophilia service, until they attend hospital. Fresh frozen plasma containing factor VIII, monoclona...
DIC will need treatment with fresh frozen plasma, cryoprecipitate and platelets. Surgical [ 5 ] It may be necessary to amputate crushed limbs.
In bleeding patients with DIC and prolonged PT and aPTT, administration of fresh frozen plasma (FFP) may be useful. It should not be started on laboratory tests alone but should be considered...
Management of coagulopathy should not be delayed [ 8 ] : Fresh frozen plasma (FFP) if activated partial thromboplastin time (aPTT) is prolonged (more than 1.5 x normal).
Infants of mothers taking drugs that inhibit vitamin K are at risk of early VKDB and should receive 1 mg IM as soon as possible after birth. [ 8 ] Classic VKDB is prevented by IM or oral administrati...
Possible administration of fresh frozen plasma and protein C concentrate to replace coagulation and anticoagulation factors, respectively [ 8 ] .
There is no evidence that fresh frozen plasma is effective in reducing bleeding and is not recommended. Extrahepatic biliary obstruction : risks of biliary peritonitis, septicaemic shock ...
Blood transfusions are necessary and correction of abnormal clotting with vitamin K and fresh frozen plasma (FFP) may also be required. Various options for treatment are available including v...
Patients frequently have a febrile reaction to granulocytes and these are more severe when amphotericin is infused at around the time of the granulocyte infusion. Fresh frozen plasma (FF...
If it is impossible to obtain adequate recombinant factor IX in time, fresh frozen plasma and cryoprecipitate may still be used. A further dose should be administered 24 hours after the fi...
Where there is C1-INH deficiency, the following are treatment options: [ 7 ] C1-INH concentrates derived from fresh frozen plasma or the recombinant C1-INH conestat alfa. Icatibant...
For initial fluid resuscitation, using starches, dextrans, albumin or fresh frozen plasma, or gelatins, versus crystalloids probably makes little or no difference to mortality. [ 6 ] For...
Currently, the treatment of HUS remains purely supportive, with no evidence for specific treatments (eg, fresh frozen plasma transfusion, heparin, urokinase, dipyridamole, Shiga toxin-binding...