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Haemophilia A (Factor VIII Deficiency), Severity of factor VIII deficiency Severity Factor VIII activity level Age of ...
Haemophilia B (Factor IX Deficiency), Synonym: Christmas disease Introduction Haemophilia B is due to a deficiency of clotting factor IX (haemophilia A is du...
Factor XIII dried [ 3 ] This is also known as human fibrin-stabilising factor and is indicated for congenital factor XIII deficiency . Adverse effects, which include allergic reactions a...
Vitamin D Deficiency, The strict use of sunscreen may increase the risk of vitamin D deficiency, particularly if high sun protection factor (SPF) creams (factor 15 ...
Iron-deficiency Anaemia, Dietary factors Not eating foods with enough iron is sometimes the cause of iron-deficiency anaemia.
Zinc Deficiency, Excess and Supplementation, What are the causes of zinc deficiency? A poor diet Zinc deficiency is more common in malnourished children and adults and...
Alpha-1 Antitrypsin Deficiency, What is alpha-1 antitrypsin deficiency? A1AT deficiency is an inherited genetic condition. A genetic condition is one that can be passed o...
Complement Deficiencies, There is also an association with SLE and possibly atherosclerosis. [ 1 ] Alternative pathway component deficiencies (properdin, factor B a...
Biotinidase Deficiency, Multiple carboxylase deficiency was described in 1971 and causes problems in the neonatal period. BTD deficiency presents in infancy. [ 1 ] Pat...
Vitamin A Deficiency, Epidemiology It is rare in the UK but is extremely common in developing countries, especially in sub-Saharan Africa and South Asia. [ 1 , 2 ] Globally, v...
Factor V Leiden Mutation Causing Thrombophilia, Heterozygous carriers have a 4- to 8-fold increased risk of VTE and homozygotes have an 80-fold increased risk. [ 1 ] The risk of VTE of a...
Vitamin B12 Deficiency and Pernicious Anaemia, Further tests are then needed to find out the cause of the vitamin B12 deficiency. These further tests include blood tests for intrinsi...
Breast Cancer Facts and Risk Factors, Dr Sarah Jarvis MBE The cause of breast cancer is probably a combination of factors. These include lifestyle factors, envi...
Protein C Deficiency, Protein C deficiency is a heritable or acquired risk factor for thrombophilia . Presentation varies from asymptomatic to venous thromboembolism to neo...
Protein S Deficiency, Excessive binding of protein S to C4b-binding protein may result in a deficiency of active protein S in the plasma. Three types of protein S deficiency...
Vitamin K Deficiency, Vitamin K deficiency is uncommon in otherwise healthy adults. Risk factors Excessive anticoagulation with coumarins - eg, warfarin. , Vit...
Vitamin K Deficiency Bleeding, This is due to deficiency of clotting factors as a result of vitamin K deficiency. Vitamin K is required for the production of c...
Alpha-1-Antitrypsin Deficiency, Evidence has shown an increased risk of liver and lung disease for people who are heterozygous for α1AT deficiency. Studies have shown that α1AT heter...
Zinc Deficiency, Excess and Supplementation, Note that phytates in wholegrain bread, cereals, legumes and some other foods inhibit zinc absorption and so affect the bioavailability of zinc fr...
Non-anaemic Iron Deficiency, (Epidemiology) Iron depletion may be three times as common as iron deficiency anaemia (IDA), which has a prevalence of 2-5% of adult men and postmenopausal wom...