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Cryoglobulinaemia, Type II and type III cryoglobulinaemia: called mixed cryoglobulinaemia (MC). They make up 75% of cryoglobulinaemias. They contain rheumatoid factor (RF), ...
The effects of the IgM which can lead to hyperviscosity syndrome, type I and type II cryoglobulinaemia, coagulation abnormalities, peripheral neuropathy, cold haemagglutinin disease (CHAD) an...
If myeloma enters complete remission then patients can be considered for renal transplantation [ 6 ] . Cryoglobulinaemia See separate Cryoglobulinaemia article. In ...
Retinoic acid therapy. Cryoglobulinaemia. Chronic hypoxia. Paraneoplastic syndromes (hyperviscosity results from the large amounts of circulating immunoglobulins, cryoglobulins, para...
Other diseases: mixed cryoglobulinaemia type II, liver cirrhosis, primary biliary cirrhosis, malignancy, after multiple immunisations, chronic sarcoidosis.
Non-hodgkin's lymphoma Chronic lymphocytic leukaemia Multiple myeloma Waldenstrom's macroglobulinaemia Monoclonal gammopathy Poems syndrome Cold autoimmune haemolytic anaemia Cryoglobulina...
Mixed cryoglobulinaemia . Renal vein thrombosis with pulmonary embolism . Investigations [ 11 , 17 ] FBC, ESR.
Positive rheumatoid factor may suggest possible cryoglobulinaemia. IgA levels are often raised in Henoch-Schönlein purpura. CXR may be carried out as part of the examination of the...
Also, glomerular pathology looking for significant immune complex deposits and vasculitis to exclude lupus glomerulonephritis, mixed cryoglobulinaemia and systemic vasculitis. Also, there ...
Hepatitis serology (types B and C are associated with PAN and mixed cryoglobulinaemia respectively). Cryoglobulins. Complement levels. Rheumatoid factor. CXR.
Differential diagnosis Pulmonary haemorrhage with renal failure can also occur in collagen vascular diseases like systemic lupus erythematosus and rheumatoid arthritis , idiopathic rapidly pr...
Differential diagnosis Warm antibody-mediated haemolytic anaemia and drug-induced haemolysis. Cryoglobulinaemia (may present with Raynaud's phenomenon but does not show haemoly...
Plasma electrophoresis may show hypergammaglobulinaemia, paraproteinaemia and cryoglobulinaemia. Autoantibody screen for connective tissue disorders. The clinical condition may indic...
Vasculitis ( polyarteritis nodosa , rheumatoid arthritis , systemic lupus erythematosus , dermatomyositis , thromboangiitis obliterans ). Cryoglobulinaemia. Antiphospholipid syndr...
Vascular disease: vasculitis (usually associated with antineutrophil cytoplasmic antibody), cryoglobulinaemia , polyarteritis nodosa , thrombotic microangiopathy, cholesterol emboli, ren...
Serum complement: low in SLE and cryoglobulinaemia and some forms of primary glomerulonephritis. Autoantibodies: ANA, anti-double stranded DNA, ANCA, antiglomerular basement membrane antib...
Abnormalities of fibrinolysis, elevated factor VIII, immune circulating complexes and cryoglobulinaemia have been occasionally reported. Leukocytosis is frequently present. The positivity of ...
It has a role in those with lymphoma, immune thrombocytopenia, vasculitic neuropathy and cryoglobulinaemias. [ 1 ] Scoring systems are used to evaluate the severity of the condition.
Glomerulonephritis . Cryoglobulinaemia . Concurrent hepatitis C infection can lead to fulminant hepatitis, more aggressive chronic hepatitis and increased risk of liver cancer.
Essential mixed cryoglobulinaemia. Polyarteritis nodosa . Autoimmune hepatitis . Thyroiditis. Membranous glomerulonephritis .