Treosulfan will be prescribed for you by a specialist doctor.
Swallow the capsules whole and drink plenty of water afterwards.
Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.
If you think you are getting an infection or if you have a high temperature, see your doctor straightaway.
|Type of medicine||Alkylating cytotoxic|
|Used for||Cancer of the ovaries|
|Available as||Capsules and injection|
Treosulfan is used to treat ovarian cancer. In cancer, certain cells in your body grow and multiply too fast. Cytotoxic medicines like treosulfan help to stop the increase in the number of these cells.
Treosulfan may be given alongside other medicines or treatments to help your condition.
Before taking treosulfan
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking treosulfan it is important that your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you have an infection or feel unwell.
- If you have porphyria (this is a rare inherited blood disorder).
- If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
- If you have ever had an allergic reaction to a medicine.
How to take treosulfan
- Treosulfan will be prescribed for you by a specialist doctor who is experienced in treating your condition. It is taken in cycles. This means that you will take the capsules every day for a number of weeks, and then have a number of weeks without them. This cycle is then repeated. Your doctor will calculate what dose is right for you and will tell you how many capsules to take and on which days to take them. It is important that you take treosulfan exactly as you have been told. If you are unsure about which weeks to take your capsules, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
- Before you start this treatment, read any printed information you have been given by your doctor and the leaflet from inside your pack of capsules. The leaflet will give you more information about treosulfan, and a full list of possible side-effects from taking it.
- Swallow treosulfan capsules whole with a drink of water. Do not chew or crush the capsules, as this may cause ulcers to develop in your mouth.
- It is important that you drink plenty of water while you are on treosulfan. This will help to prevent a serious type of cystitis which is sometimes caused by this medicine.
- If you are sick shortly after taking a dose, or if you forget a dose, contact your doctor or clinic for advice of what to do.
Getting the most from your treatment
- You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests during your treatment with treosulfan.
- Like other medicines that are taken to treat cancer, it is important that you do not get pregnant while you are taking treosulfan. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner if this is applicable for you.
- While you are taking treosulfan and for a while after you stop treatment, do not have any immunisations (vaccinations) without talking to your doctor first. Treosulfan lowers your body's resistance and there is a chance that you may get an infection from some vaccines.
Can treosulfan cause problems?
Treosulfan can lower the number of white cells in your blood, increasing the chance of you getting an infection. You should take certain precautions to reduce the risk of infection - if possible, avoid people with infections and let your doctor know if you think you are getting a sore throat or if you have a high temperature.
Your doctor will discuss with you the possibility of other unwanted side-effects of treosulfan treatment. Let your doctor know if you experience any of the following:
|Very common treosulfan side-effects - these affect more than 1 in 10 people who take this medicine
||What can I do if I experience this?|
|Feeling or being sick||Stick to simple meals. If this becomes troublesome, let your doctor know, as you can be prescribed an anti-sickness medicine|
|Some loss of hair; a bronze skin colouration||Discuss these with your doctor if you are concerned|
Important: occasionally, treosulfan can cause cystitis and breathing problems. If you experience any problems passing urine, or if you feel short of breath, let your doctor know about these things straightaway.
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store treosulfan
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Further reading & references
- British National Formulary; 64th Edition (Sep 2012) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (links to current BNF)
|Original Author: Helen Allen||Current Version: Helen Allen||Peer Reviewer: Dr Helen Huins|
|Last Checked: 10/12/2012||Document ID: 3617 Version: 23||© EMIS|
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.