Levothyroxine


  • You will need regular blood tests to check your thyroid levels in the early stages of treatment.
  • Do not take levothyroxine at the same time as indigestion remedies or preparations containing calcium or iron.
  • If you experience any side-effects, speak with your doctor as your dose may need adjusting.
Type of medicine Thyroid hormone
Used for Hypothyroidism
Also called Levothyroxine sodium
Eltroxin®
Evotrox®
Available as Tablets and oral liquid

Levothyroxine is the same as the hormone thyroxine which is produced in the body by the thyroid gland. Levothyroxine is given when the thyroid gland is not producing enough thyroxine.

Before taking levothyroxine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have heart problems or high blood pressure.
  • If you know you suffer from adrenal insufficiency (this is where your adrenal gland is unable to produce enough of the hormone cortisol).
  • If you have diabetes mellitus (sugar diabetes) or diabetes insipidus.
  • If you have been told your thyroid gland produces too much thyroid hormone.
  • If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.
  • Before starting this treatment, read the manufacturer's printed information leaflet.
  • Take levothyroxine exactly as your doctor has told you.
  • Levothyroxine is usually taken once daily, before breakfast.
  • If you forget to take a dose, take it as soon as you remember if this is within 2 or 3 hours of your usual time. If you do not remember until after this time, skip the forgotten dose. Do not take two doses together to make up for a missed dose.
  • Keep your regular appointments with your doctor so your progress can be monitored. You will need regular blood tests to check your thyroid levels in the early stages of your treatment.
  • If you buy any medicines, check with a pharmacist that they are safe to take with levothyroxine. Levothyroxine should not be taken at the same time as indigestion remedies or preparations containing calcium or iron (which are contained in some vitamin products) as these can reduce the amount of levothyroxine absorbed by your body. Leave at least 2 hours between your dose of levothyroxine and any such preparations.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment that you are taking levothyroxine.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects become troublesome as your dose of levothyroxine may need to be adjusted.

Possible side-effects What can I do if I experience this
Feeling or being sick Eat little and often. Stick to simple foods
Diarrhoea Drink plenty of water to replace lost fluids
Headache Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know
Palpitations or chest pain Let your doctor know about this
Restlessness, flushing, sweating, difficulty sleeping, fever, loss of weight, cramps, temporary loss of hair If any of these become troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 60th Edition (September 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
  • Manufacturer's PIL, Eltroxin® 25mcg, 50mcg and 100mcg Tablets; Manufacturer's PIL, Eltroxin® 25mcg, 50mcg and 100mcg Tablets, Goldshield plc, electronic Medicines Compendium. Dated December 2010.
Original Author: Helen Allen Current Version:
Last Checked: 26/01/2011 Document ID: 3214  Version: 23 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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