Ketoprofen (topical)

  • Ketoprofen should be applied with gentle massage only.
  • Wash your hands after applying the gel.
  • Protect any treated areas from sunlight during treatment with topical ketoprofen and for two weeks afterwards.
Type of medicine Topical non-steroidal anti-inflammatory drug (NSAID)
Used for Treating pain and swelling due to strains, sprains, backache or arthritis
Also called Oruvail®
Powergel®
Tiloket®
Available as Topical gel

Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) and works by preventing the production of chemicals which cause pain and inflammation in the body. It is used topically (applied directly onto the skin) to ease muscular pains, sprains and strains.

Before using topical ketoprofen make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you suffer from asthma or breathing problems.
  • If you have ever had an unusual reaction after taking aspirin or any other non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen, diclofenac or naproxen.
  • If you have allergy problems.
  • If you have eczema or a skin infection.
  • If you have severe kidney problems.
  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Apply a thin layer of the gel and gently massage it into the affected area. Wash your hands well afterwards.
  • Your doctor or pharmacist will recommend how often and for how long to use the gel, but this is usually up to four times a day and for no more than 7 days.
  • Avoid the gel coming into contact with your eyes, inside your nose, and any inflamed or broken skin.
  • Do not use this gel on any area that is covered by a bandage, dressing or sticking plaster.
  • If you forget to apply ketoprofen at your usual time, apply it as soon as you remember.
  • Do not use sunbeds, and even on cloudy days protect any treated areas from sunlight. This is because the treated area of skin may become more sensitive to sunlight during treatment and for 2 weeks afterwards.
  • Ketoprofen gel is not suitable for use in children under 12 years of age.

Along with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Possible side-effects What can I do if I experience this
Itching or reddening of the skin at the site of application If severe, stop using the gel and this should clear within a day or two. If it continues or gets worse, consult your doctor as soon as possible
  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Before using this medicine tell your doctor if you are pregnant, trying for a baby or breast-feeding.
  • If you suspect that you or someone else has swallowed some of this gel, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having any treatment like an operation or dental treatment tell the person carrying out the treatment which medicines you are taking.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 59th Edition (March 2010) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
  • Manufacturer's PIL, OruvailĀ® Gel 2.5%; Manufacturer's PIL, OruvailĀ® Gel 2.5%, sanofi-aventis, electronic Medicines Compendium. Dated November 2008.
  • Manufacturer's PIL, Powergel 2.5% gel, A.Menarini Pharma U.K. S.R.L., electronic Medicines Compendium. Dated October 2009.
Original Author: Helen Allen Current Version:
Last Checked: 18/11/2010 Document ID: 998  Version: 23 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

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