Indoramin - an alpha-blocker - Doralese

Indoramin is prescribed for two different medical conditions: 20 mg strength tablets are prescribed for men with prostate problems, and 25 mg strength tablets are prescribed for people with high blood pressure.

You are advised not to drink alcohol while you are on indoramin.

Do not drive or use tools or machines if you feel tired or dizzy.

Type of medicine An alpha-blocker
Used for Enlargement of the prostate gland; and hypertension (high blood pressure)
Also called Doralese® (for prostate gland enlargement)
Available as Tablets

Indoramin belongs to a group of medicines known as alpha-blockers. It works by blocking the action of certain nerve impulses. This blocking action is useful in two different medical conditions. It is used to help control the symptoms of prostate gland enlargement, and it also reduces blood pressure in people with hypertension (high blood pressure).

The prostate gland commonly becomes larger in older men. Prostate gland enlargement is also called benign prostatic hyperplasia (BPH). It can cause problems with passing urine, such as having to wait before your urine starts to flow, taking longer at the toilet, dribbling, and a feeling that your bladder is not quite empty. Indoramin works by relaxing the muscles around your bladder and prostate so that you can pass urine more easily.

In people with high blood pressure, indoramin works by relaxing blood vessel walls. This allows blood and oxygen to circulate more freely around your body and lowers your blood pressure.

There are two strengths of indoramin available - 20 mg tablets will be prescribed for men with prostate problems, and 25 mg tablets will be prescribed for people with high blood pressure.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking indoramin it is important that your doctor knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you ever feel dizzy or faint when you stand up, or if you have ever fainted after passing urine.
  • If you are due to have cataract eye surgery.
  • If you have any problems with the way your liver works, or any problems with the way your kidneys work.
  • If you have been told you have heart failure.
  • If you have epilepsy or Parkinson's disease, or if you have ever been diagnosed with depression.
  • If you have ever had an allergic reaction to a medicine.
  • If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, such as herbal and complementary medicines.
  • Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about indoramin and will provide you with a full list of the side-effects which you may experience from taking it.
  • When you first start the treatment, your doctor may give you a low dose which will then later be increased. This allows your doctor to make sure that you have the dose that helps your condition and avoids any unwanted symptoms.
  • It is usual to take indoramin twice a day. Try to take your doses at the same times of day each day, as this will help you to avoid missing doses.
  • Swallow the tablet with a drink of water. You can take indoramin before or after meals.
  • If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.
  • Indoramin can make you feel sleepy, particularly when you first start taking it. Make sure your reactions are normal before you drive or use tools or machines.
  • You are advised not to drink alcohol while you are on indoramin. Alcohol interferes with how much of the medicine your body absorbs. It can also increase the risk of side-effects such as feeling drowsy.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • If you are having an operation or medical treatment, tell the person carrying out the treatment that you are taking indoramin. This is because your blood pressure may drop suddenly with an anaesthetic. If you are having cataract surgery, it is particularly important that you tell your eye surgeon that you are on indoramin. This is because an eye problem known as 'floppy iris syndrome' has developed in some people taking medicines similar to indoramin, so your doctor may advise that you stop taking it for a short while.
  • If you buy any medicines check with a pharmacist that they are suitable to take with your other medicines. Some anti-inflammatory painkillers (called NSAIDs) can reduce the blood pressure lowering effect of indoramin.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with indoramin. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Indoramin side-effects
What can I do if I experience this?
Feeling drowsy, dizzy or faint If any of these happen, do not drive or use tools or machines until you feel better. Do not drink alcohol
Headache Ask your pharmacist to recommend a suitable painkiller
Dry mouth Try chewing sugar-free sweets or sugar-free gum
Swollen feet or ankles, blocked nose, increase in weight, sexual problems, and feeling depressed If any of these become troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine, ask your pharmacist.

Further reading & references

  • British National Formulary; 67th Edition (March 2014) British Medical Association and Royal Pharmaceutical Society of Great Britain, London

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

Original Author:
Helen Allen
Current Version:
Peer Reviewer:
Dr Adrian Bonsall
Last Checked:
28/05/2014
Document ID:
3376 (v24)
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