Advertising Survey

We would like your input on how advertising is currently used in the site.

Please take this short survey to help us out.

Hide this message

Zolmitriptan

  • Zolmitriptan is used to treat migraine headaches.
  • You may experience sensations of tightness or heaviness in your chest after taking zolmitriptan. These sensations usually do not last long, but if they continue or become intense, stop taking zolmitriptan and contact your doctor as soon as possible.
  • Do not take other migraine treatments while you are taking zolmitriptan.

About zolmitriptan

Type of medicine5HT1-receptor agonist (also known as a 'triptan')
Used forTreatment of migraine
Also calledZomig®
Zomig® Rapimelt
Available asTablets
Orodispersible (melt-in-the-mouth) tablets
Nasal spray

It is not clear what causes migraine. It is thought that some chemicals in the brain increase in activity, and as a result parts of the brain then send out confused signals which result in the symptoms of migraine.

It is also not clear why people with migraine should develop these chemical changes and most migraine attacks occur for no apparent reason. In some people however, there may be things which trigger an attack, like certain foods or drinks.

Zolmitriptan works by stimulating the receptors of a chemical in the brain, called serotonin (or 5HT). This improves the symptoms felt during a migraine.

Before taking zolmitriptan

Before taking zolmitriptan make sure your doctor or pharmacist knows:

  • If you are aged over 65 years or under 18 years old.
  • If you are pregnant, trying for a baby or breast-feeding.
  • If you have heart or heart rhythm problems.
  • If you have recently had a heart attack.
  • If you have high blood pressure.
  • If you have liver problems.
  • If you have ever had a stroke or a transient ischaemic attack (also referred to as a TIA or 'mini-stroke').
  • If you have ever had an allergic reaction to this or to any other medicine.
  • If you are taking any other medicines, including those available to buy without a prescription, herbal and complementary medicines.

How to take zolmitriptan

  • Take zolmitriptan exactly as your doctor has told you.
  • Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
  • Make sure you know how to administer the preparation you have been given.
  • If you have been supplied tablets: take one dose as soon as possible at the first sign of an attack. If your migraine improves but then returns, you may take one further dose, providing it is at least two hours after the initial dose. Do not take more than two doses in any 24-hour period.
  • To use Zomig® Rapimelt tablets, peel open the foil blister and remove the tablet. Place it on your tongue and allow it to dissolve before you swallow.
  • If you have been supplied a nasal spray: spray one puff into one nostril at the first sign of an attack. If your migraine improves but then returns, one further spray can be used in one nostril, providing it is at least two hours after your first dose. Do not administer more than two sprays in any 24-hour period.
  • To use the nasal spray, remove the protective cover and block one nostril by pressing on it with your finger. Insert the spray into the other nostril and breathe in through your nose as you squeeze the plunger to release one dose.

Getting the most from your treatment

  • Zolmitriptan is used to treat a migraine once it has started, but there are other medicines that are available that may help to prevent you having migraines. If you have migraines frequently, discuss this with your doctor.
  • Do not take other migraine treatments (such as other 'triptans' or ergotamine) as well as zolmitriptan.
  • If you find that zolmitriptan does not relieve your migraine, make an appointment to discuss this with your doctor, as an alternative preparation may prove to be more effective for you.
  • If you buy any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside zolmitriptan.

Can zolmitriptan cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this?
Dry mouthTry chewing sugar-free gum or sugar-free sweets
Feeling or being sick, stomach painStick to simple foods
Feeling sleepy, dizzy or weakIf this happens, do not drive or use tools or machines
Pressure or tightness in any part of the body, including the throat or chestIf these feelings continue or become intense, stop taking zolmitriptan and contact your doctor as soon as possible
Tingling feelings, headache, feeling hot or flushed, an uneven heartbeat, muscle weaknessIf any of these become troublesome, speak with your doctor

If you experience any other symptoms which you think may be due to this medicine, discuss them with your pharmacist or doctor.

How to store zolmitriptan

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

  • Never take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment tell the person carrying out the treatment which medicines you are taking
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist

References

The pharmacists and clinicians responsible for the production of this document are:
Original Author: Helen Allen
Last Checked: 16 Nov 2011
Current Version: Helen Allen
Document ID: 1520  Version: 27
Peer Reviewer: Dr Adrian Bonsall
© EMIS 2011
Provide feedback