Before taking varenicline

Before taking varenicline make sure your doctor or pharmacist knows:

• If you are under 18 years of age.
• If you have ever had a mental health problem such as depression.
• If you have ever had heart or blood vessel problems.
• If you have kidney problems.
• If you are pregnant, trying for a baby or breast-feeding.
• If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
• If you have ever had an allergic reaction to this or to any other medicine.

How to take varenicline

• Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack.
• Take varenicline exactly as your doctor has told you.
• Start taking the tablets one week before your quit date. The aim is to build up the dose so your body gets used to the varenicline before the quit date. The usual advice is to start with one white tablet (500 micrograms) daily for the first three days. Then one white tablet (500 micrograms) twice daily on days four to seven. Then, one blue tablet (1 mg) twice daily for 11 weeks.
• You can take varenicline tablets before or after meals.
• Try to take varenicline at the same time(s) each day to avoid missing any doses.
• If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

Getting the most from your treatment

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
• Varenicline may affect your concentration and cause you to feel dizzy. If this happens, do not drive or use tools or machines.
• The usual course of treatment is for 12 weeks (although in some cases an additional 12 weeks of treatment may be advised). After this time, your doctor may suggest you reduce your dose over a week or so. This is because at the end of treatment if varenicline is stopped suddenly there may be problems, such as an urge to smoke, depression, and/or sleeping difficulties, for a short time. These problems can be eased by a gradual reduction of your dose.
• Varenicline will help you to give up smoking, but you still need determination to succeed and to break the smoking habit. If you are still smoking after 12 weeks, discuss this with your doctor.
• Speak with your doctor for advice about taking varenicline and alcohol. You may be advised not to drink alcohol while you are being treated with varenicline.
• If you buy any medicines, check with a pharmacist that they are safe to take with varenicline.
• This medicine is for you. Never give it to others, even if their condition appears to be the same as yours.

Can varenicline cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

How to store varenicline

• Keep all medicines out of the reach and sight of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

References

• Manufacturer's PIL, Champix® 0.5 mg film-coated tablets; Champix® 1 mg film-coated tablets, Pfizer Limited, electronic Medicines Compendium. Dated November 2011.
• British National Formulary; 62nd Edition (Sep 2011) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF)