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Trientine

  • Take trientine capsules half to one hour before meals.
  • Do not take indigestion remedies or preparations containing iron or zinc at the same time.

About trientine

Type of medicineChelating agent
Used forWilson's disease
Also known asTrientine dihydrochloride
Available asCapsules

Wilson's Disease is a genetic disorder in which copper builds up in the body, mainly in the liver and brain. Treatment is with medication to remove the excess copper and/or to prevent a further build-up of copper.

Trientine is used to treat Wilson's disease and works by helping the body remove the excess copper.

Before taking trientine

Before taking trientine make sure your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breast-feeding.
  • If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
  • If you have ever had an allergic reaction to this or any other medicine.

How to take trientine

  • Before beginning treatment, read the manufacturer's printed information leaflet.
  • Take trientine exactly as directed by your doctor. Take the capsules half to one hour before food.
  • Do not take indigestion remedies or medicines containing iron or zinc at the same time as trientine. Leave at least two hours before or after a dose of trientine before taking these.
  • Try to take trientine at the same times each day to avoid missing any doses. If you do forget to take a dose, take one as soon as you remember.

Getting the most from your treatment

  • Keep any regular doctor's appointments so your progress can be monitored.
  • Do not stop taking this medicine without speaking to your doctor first.
  • If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
  • If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.

Can trientine cause problems?

Along with their useful effects all medicines can cause unwanted side-effects. These usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common side-effects - these affect less than 1 in 10 people who take this medicineWhat can I do if I experience this
Feeling sickEat little and often. Stick to simple foods
Skin rashIf this is severe or troublesome, let your doctor know

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

How to store trientine

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines


  • Never take more than the prescribed dose. If you suspect that you or someone else has taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

References

  • British National Formulary; 58th Edition (September 2009) British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
Comprehensive patient resources are available at www.patient.co.uk
© EMIS 2010DocID: 3791DocRef: dils3799Last Reviewed: 2 Jun 2010Version: 22
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