Silver sulfadiazine for skin infections

  • Tell your doctor before using this cream if you have ever had an allergic reaction to a sulfonamide antibiotic.
  • Once opened, the cream has an expiry date of seven days. Do not use it after this time.
Type of medicine An anti-infective skin cream
Used for Skin infections such as infected burns
Also called Flamazine®
Available as Cream

Silver sulfadiazine cream is used to prevent or to treat bacterial infections affecting your skin. It is particularly helpful in preventing burns from becoming infected. It works by killing the bacteria which are responsible for skin infections.

To make sure this is the right treatment for you, before you start using silver sulfadiazine it is important that your doctor or pharmacist knows:

  • If you are pregnant or breast-feeding.
  • If you have ever had an allergic reaction to any medicine. It is particularly important that you tell your doctor if you have had a bad reaction to a sulfonamide medicine in the past. (Sulfonamides are mainly used to treat infections.)
  • If you have liver or kidney problems.
  • If you have glucose-6-phosphate dehydrogenase deficiency. This is an hereditary condition where there is a lack of an enzyme often known as G6PD.
  • If you are using any other preparations, including those available to buy without a prescription, herbal and complementary medicines.
  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about the cream and a full list of possible side-effects from using it.
  • Depending upon the reason you are using the cream, you may be directed to use it each day or several times a week. Your doctor will tell you how often is right for you, and this information will also be on the label of your pack.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common silver sulfadiazine side-effects - these affect less than 1 in 10 people who use the cream What can I do if I experience this?
Itching, or a burning feeling Speak with your doctor if this continues
Skin rash Speak with your doctor about this as soon as possible

Important: rarely, silver sulfadiazine may cause blood disorders and skin discolouration. If you are using the cream over a long period of time or on large areas of your skin, your doctor will check for this. However, if at any time during your treatment you begin to feel generally unwell, you should speak with your doctor for advice.

  • Keep all medicines out of the reach and sight of children.
  • Store in a cool, dry place, away from direct heat and light.
  • Tubes of Flamazine® only keep for seven days once opened. Do not use or store the cream after this time.
  • Make sure that the person prescribing this medicine knows about any other medicines that you are taking. This includes medicines you buy and herbal and homeopathic medicines.
  • If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
  • Never use more than the prescribed dose. If you suspect that someone has swallowed some of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.
  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking or using.
  • This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
  • Never keep-out-of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
  • If you have any questions about this medicine ask your pharmacist.

Further reading & references

  • British National Formulary; 63rd Edition (Mar 2012) British Medical Association and Royal Pharmaceutical Society of Great Britain, London
Original Author: Helen Allen Current Version: Peer Reviewer: Dr Adrian Bonsall
Last Checked: 18/05/2012 Document ID: 3737  Version: 23 © EMIS

Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions.

The Information Standard - certified member

The authors and editors of this article create up to date content reflecting reliable research evidence, guidance and best clinical practice. Learn more

Advertisements