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Ropinirole
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About ropinirole
| Type of medicine | Dopamine receptor stimulant |
| Used for | Parkinson's disease Restless legs syndrome |
| Also called | Adartrel® Requip®, Requip® XL |
| Available as | Tablets and modified release tablets (ropinirole is released slowly to give an even effect) |
Ropinirole can be used to treat Parkinson's disease. The cause of Parkinson's disease is still unknown, but it results in there being less of a chemical in the brain called dopamine. This lack of dopamine causes the symptoms of Parkinsonism such as shaking, stiffness and loss of muscle control. Ropinirole encourages the release of dopamine, relieving these symptoms. It may be used alone or in combination with other medicines used to treat Parkinson's disease.
Ropinirole can also be used to treat restless legs syndrome. This is an uncomfortable feeling in the legs which is temporarily relieved by moving the legs. Symptoms come on when resting and are worse at the end of the day.
Before taking ropinirole
Before taking ropinirole make sure your doctor or pharmacist knows:
- If you are pregnant, trying for a baby or breast-feeding.
- If you suffer from a heart or blood vessel disorder.
- If you suffer from liver or kidney problems.
- If you have ever suffered from mental health problems.
- If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
- If you have ever had an allergic reaction to this or any other medicine.
How to take ropinirole
- Before beginning treatment, read the manufacturer's printed information leaflet.
- Take your medication exactly as directed by your doctor. Swallow your dose with a small glass of water.
- Take the immediate release tablets (e.g. Adartrel® and Requip®) after eating a meal. The modified release tablets (Requip® XL) can be taken either before or after meals.
- Try to take ropinirole at the same times each day to avoid missing any doses.
- If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.
Getting the most from your treatment
- As your condition improves and your body movements become easier, be careful not to overdo physical activities. Physical activities must be increased gradually to allow your body to adjust to changing balance, circulation and co-ordination. This is especially important in the elderly.
- Keep your regular doctor's appointment so your progress can be monitored.
- Do not stop taking this medicine without speaking to your doctor first. Your dose will need to be reduced gradually.
- If for any reason you haven't taken your medicine for a few days, speak to your doctor.
- If you buy any medicines, check with a pharmacist that they are safe to take with ropinirole.
Can ropinirole cause problems?
Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.
| Common side-effects - these affect less than 1 in 10 people who take this medicine | What can I do if I experience this |
| Drowsiness, sleepiness, dizziness | Make sure you know how you react to this medicine before driving, operating machinery, or doing any other jobs which could be dangerous if you were not fully alert |
| Dizziness or fainting, especially when getting up from a sitting or lying position | Getting up slowly should help. If you begin to feel dizzy, lie down so that you do not faint, then sit for a few moments before standing |
| Feeling or being sick | Eat little and often. Stick to simple foods such as dry toast. Drink plenty of liquids to replace any lost fluid |
| Constipation | Eat a well balanced diet containing plenty of fibre and drink 6-8 glasses of water a day |
| Swollen legs and ankles, abdominal pain, indigestion, nervousness, tiredness, uncontrollable movements of the face or body, seeing or hearing things that are not real, or confusion. | If any of these are troublesome, speak with your doctor |
Important: Speak to your doctor if you notice any changes in your behaviour such as an increased desire to gamble or an increased sex drive.
If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.
How to store ropinirole
- Keep all medicines out of the reach of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
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References
- Manufacturer's PIL, Requip®, GlaxoSmithKline UK, electronic Medicines Compendium. Revised December 2006, accessed 18 March 2008.
- Manufacturer's PIL, Adartrel®, GlaxoSmithKline UK, electronic Medicines Compendium. Revised June 2007, accessed 18 March 2008.
- British National Formulary; 54th Edition (September 2007) British Medical Association and Royal Pharmaceutical Society of Great Britain, London (link to current BNF).
The authors and editors of this article are employed to create accurate and up to date content reflecting reliable research evidence, guidance and best clinical practice. They are free from any commercial conflicts of interest. Find out more about updating.
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