Rifabutin

About rifabutin

Rifabutin is an antibiotic used to treat infections including tuberculosis (also known as TB). It is used for TB in combination with several other antibiotics. It can also be used on its own to prevent infections occurring in those with a lowered immune system (people more prone to infection).

Before taking rifabutin

Before taking rifabutin make sure your doctor or pharmacist knows:

• If you are pregnant, trying for a baby or breast-feeding.
• If you have liver problems, including jaundice (yellowing of the skin and whites of the eyes).
• If you have kidney problems.
• If you have porphyria (a blood disorder).
• If you are taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
• If you have ever had an allergic reaction to this or any other medicine.

How to take rifabutin

• Before beginning treatment, read the manufacturer's printed information leaflet.
• Take your medication exactly as directed by your doctor.
• You must complete the course of rifabutin.
• Do not stop taking rifabutin without speaking to your doctor first
• Try to take rifabutin at the same time each day to avoid missing any doses.
• If you forget to take a dose, take one as soon as you remember unless it is nearly time for your next dose. Do not take two doses at the same time to make up. If in doubt, speak to your pharmacist or doctor.

Getting the most from your treatment

• Important: rifabutin reduces the effects of oral contraception. You should use an alternative method of contraception such as an intra-uterine device (IUD) or condom while taking this medication and for up to eight weeks after completing the course. Speak to your doctor for advice.
• This medicine may colour urine, saliva and other body fluids orange-red. This is completely harmless and should be no cause for concern.
• Rifabutin can cause discolouration of soft contact lenses and you should not wear these during treatment.
• You must keep your regular appointments with your doctor. You will need to have regular blood and urine tests while taking rifabutin.
• If you buy any medicines, check with a pharmacist that they are safe to take with your other medicines.
• Do not stop taking this medicine without speaking to your doctor first.

Can rifabutin cause problems?

Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. Speak with your doctor or pharmacist if any of the following side effects continue or become troublesome.

How to store rifabutin

• Keep all medicines out of the reach of children.
• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines